LAB 4

Question 1

Ideal area of examination

Answer 1

Thin area

Question 2

Thin area features

Answer 2

Even distribution of erythrocytes
RBCs are slightky separated from one another or barely touching without overlapping
RBCs are circular with smooth edge and central pale area (reddish-pink cytoplasm)

Question 3

red cell distribution is irregular with artifactual shapes and colors and size distortions

Answer 3

Feather end

Question 4

unsuitable for examination

Answer 4

Thicker Portion

Question 5

thicker portion features

Answer 5

red cells may overlap or lie on top of one another

Question 6

Rouleaux Formation

Answer 6

RBCs appear in short or long stacks resembling coins or flat plates

Question 7

concentration of plasma gamma globulin and fibrinogen in Rouleaux Formation

Answer 7

Increased

Question 8

Rouleaux Formation ESR

Answer 8

increased

Question 9

rouleaux formation clinical association

Answer 9

Multiple myeloma
hyperproteinemia
macroglobulinemia

Question 10

agglutination

Answer 10

rbcs aggregate when exposedto red cell antibodies

Question 11

autoagglutination

Answer 11

rbcs agglutinate when exposed to individual’s own antibodies

Question 12

agglutination rbc count

Answer 12

decreased

Question 13

agglutination rbc parameters

Answer 13

increased mcv,mch,mchc

Question 14

agglutination clinical association

Answer 14

cold agglutinin disease
hemolytic anemia
staphylococcal infections
tryoanosomiasis
priimaty atypical pneumonia (M,pneumoniae):autoanti-I

Question 15

normal rbc shape

Answer 15

biconcave disc (discocyte)

Question 16

rbc average diameter

Answer 16

6-8 um or 7-8 um

Question 17

average thickness

Answer 17

2.5 um

Question 18

average volume rbc

Answer 18

90 fL

Question 19

rbc average surface area

Answer 19

140 um^2

Question 20

rbc inclusions

Answer 20

none

Question 21

variation in erythrocyte size

Answer 21

anisocytosis

Question 22

variation in the normal coloration of erythrocytes

Answer 22

anisochromia

Question 23

variation in red cell shape

Answer 23

poikilocytosis

Question 24

6-8 um | MCV= 80-100 fL

Answer 24

Normocytic RBC

Question 25

<6 um | MCV <80 fL

Answer 25

Microcytic RBC

Question 26

>8 um | MCV = > 100 fL

Answer 26

Macrocytic RBC

Question 27

normocytic rbc associated clinical conditions

Answer 27

acute blood loss hemolytic anemia aplastic anemia

Question 28

microcytic rbc associated clinical conditions

Answer 28

IDA,Thalassemia,Anemia of Chronic Inflammation, Sideroblastic(occasional)

Question 29

macrocytic rbc associated clinical conditions

Answer 29

megaloblastic anemia macrocytic anemia myelodysplastic syndrome chronic liver disease bm failure chronic hemolytic anemia with reticulocytosis sideroblastic anemia mycoplasma pneumoniae infection alcoholism cancer chemotherapy

Question 30

index of variation of cell volume & correlates with the degree of anisocytosis

Answer 30

red cell distribution width

Question 31

CV of RBC Cell distribution

Answer 31

RDW

Question 32

RDW=

Answer 32

SD/Mean of red cell distribution

Question 33

normal range of rdw

Answer 33

11.5 -14.5 %

Question 34

increased rdw

Answer 34

anisocytosis heterogeneous red cell size

Question 35

normal rdw

Answer 35

homogenous red cell size

Question 36

anisochromia is caused by

Answer 36

unequal hgb concentration