lec 10 Flashcards

1
Q

the mucosa of the uterine tubes is composed of

A

simple columnar epithelium ciliated and non-ciliated secretory cells
and a lamina propria loose connective tissue

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2
Q

the Muscular layer of uterine tube is composed of

A

inner circular and an outer longitudinal

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3
Q

the uterine tube is covered by (serosa or adventitia)

A

Serosa: Visceral peritoneum

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4
Q

Makes up bulk of uterus ?

A

Myometrium

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5
Q

how many layers does the myometrium form ? and are they distinguished ? arrangement ?

A

4 no they are ill defined
1-4 longitudinal
2-3 circular

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6
Q

the increase of myometrial size due to response to estrogen is mainly caused by ?

A

hypertrophy (increase in size

although some hyperplasia might occur

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7
Q

endometrium is made of which type of cells ?

A

simple columnar epithelium contains two types of cells, ciliated and non-ciliated secretory cells

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8
Q

At end of menstrual phase, endometrium is usually reduced to

A

thin layer of lamina propria, deep ends of uterine glands, and some covering epithelium.

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9
Q

what type of glands do we find in uterus and in which layer of endometrium ?

A

Simple tubular glands they sometimes branch in their deeper portions

lamina propria

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10
Q

what is the epithelial lining of glands

A

simple columnar epithelium but the ciliated are rare in glands

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11
Q

how many days does the Proliferative phase

A

10

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12
Q

the menstrual phase is caused by ?

A

Failure of fertilization ovum leads to inhibition in production of progesterone by corpus luteum

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13
Q

when does the secretory phase start ? for how long ?

A

Start at ovulation and lasts about 14 days

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14
Q

the secretory phase results from action of ?

A

progesterone secreted by corpus luteum

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15
Q

describe the glands in the secretory phase and proliferative

A

proliferative –> straight tubules with narrow lumen

secretory –> dilated tubules highly coiled

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16
Q

what causes the dilation of the lumen of the glands in the secretory phase

A

glycoprotein secretory products dilate lumens of glands

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17
Q

In this phase endometrium reaches its maximum thickness

A

secretory phase

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18
Q

Mitosis is rarely seen during this phase (uterine)?

A

secretory phase

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19
Q

Cervix Is lined by

A

simple, high columnar mucous-secreting epithelial cells

20
Q

The external surface of the cervix that bulges into lumen of vagina is covered with

A

stratified squamous epithelium

21
Q

which type is the cervical mucous glands

A

extensively branched

22
Q

describe the mucous secretions from the cervix in these phases
secretory phase or in pregnancy ?
At time of ovulation?
mention the reason

A

proliferate and secrete a more viscous and abundant mucous , because of progesterone

mucous secretions are watery

23
Q

the mucosa of the vagina is lined by ?

A

stratified squamous

24
Q

the mucosa of the vagina contains many ———– bit it is devoid of ————–

A

elastic fibers

devoid of glands

25
Q

what is the effect of estrogen on vagina

A

vaginal epithelium synthesizes and accumulates a large quantity of glycogen, which is excreted into lumen of vagina.

26
Q

what causes the low PH of the vagina ?

A

Bacteria metabolize glycogen and form lactic acid

27
Q

The wall of vagina consists of

A

inner mucosa layer, a middle muscular layer, and an outer dense connective tissue layer, adventitia

28
Q

Muscular layer of the vagina is made of

A

ill defined

inner circular outer longitudinal

29
Q

The gonads appear initially at

A

5th week

30
Q

Primordial germ cells migrate from

A

yolk sac

31
Q

Primordial germ cells reach the primitive gonads beginning of week ——— and invading genital ridges in ————–

A

5

6th W

32
Q

the gonadal ridges lie

A

on the medial surface of mesonephros

33
Q

Gonads (testes and Ovaries) are derived from three sources

A

(1) Mesothelium (mesodermal epithelium) lining the posterior abdominal wall.
(2) Underlying mesenchyme (embryonic connective tissue).
(3) Primordial germ cells

34
Q

which part of the indifferent gonad differentiate
XY –>
XX –>

A

medulla differentiates into testis, while cortex regresses

cortex differentiates into ovary, while medulla regresses

35
Q

gonads of two sexes are identical and called indifferent gonads until week ———-

A

7

36
Q

In male, under influence of —————–, the gonadal cords continue to proliferate and penetrate deep into medulla
to form ————

A

testis-determining factor (TDF)

medullary or seminiferous cords

37
Q

seminiferous cords become continuous at their extremities with rete testis in ——— month

A

4

38
Q

Sertoli cells derived from

A

surface epithelium of gland

39
Q

The Sertoli cells produce what ?until when ? that does what ?

A

mullerian inhibiting substance (MIS) until puberty

suppress development of paramesonephric ducts, which form uterus and uterine tubes

40
Q

Interstitial (leydig) cells , derived from what? and lies where?

A

original mesenchyme of gonadal ridge, lie between semineferous cords.

41
Q

Seminiferous cords are composed of ?

A

spermatogonia

sertoli cells

42
Q

By————– week leydig cells begin production of ————–

A
8th W
androgenic hormones (testosterone)
43
Q

Seminiferous cords remain solid until

A

puberty

44
Q

Testosterone production is stimulated by

A

human chorionic gonadotropin (GTH).

45
Q

hCG reaches peak amount during the ——- period of fetal development

A

8 – 12 W