Lec 17 Mitochondrial Density

Question 1

Training particularly endurance training will increase what?

Answer 1

Increase mitochondrial volume density

Question 2

Mitochondrial content continues to increase if ?

Answer 2

Workload is progressive

Question 3

An increase in which complex’s leads to an increase in mitochondrial content

Answer 3

II and IV

Question 4

Skeletal muscles adapt to endurance training

Increased what?
What happens to substrate utilization at the SAME work load?
What happens to lactate production?
What happens to RER

Answer 4

Mitochondrial content
Use more fat and less carbs
Decreased lactate production
Decreased RER

Can maintain fat oxidation at higher intensities

Question 5

What happens to lactate threshold with training

Answer 5

Improved lactate threshold

Gets pushed to a higher power output

Decrease lactate production with training at the same power output

Question 6

Why does fuel use change with training?

Answer 6

Less carb use, less glycogenolysis

A LOWER ADP, AMP, AND EPINEPHRINE
REDUCED ACTIVATION OF PHOS AND PFK ENZYMES

Muscle glycogen is spared
Glucose oxidized is decreased
Lactate production is decreased

Question 7

True or false

Mitochondria and vo2max decrease at the same rate

Answer 7

FALSE

Question 8

What happens in one week of not training

Answer 8

Decrease in 50% of mitochondrial capacity

If you don’t use it you lose it

Lose it quicker than you build it

Question 9

After one session of high intensity interval training what happens to glucose

Answer 9

Decrease glucose levels up to 24 hrs

Good for type two diabetes

Question 10

What stage do you translocate glut4

Answer 10

Early exercise

However late exercise has the most

Question 11

What stage do you use the most glucose

Answer 11

Late exercise

Question 12

What happens to glycogen early and post exercise

Answer 12

Early
- glycogen is the main source of energy right in the muscle with the use of glycogenolysis

Post
- glycogen is depleated
Glucose uptake increases to restore glycogen stores

Question 13

Why is it important that glut4 stays on the membrane late to post exercise

Answer 13

Helps reduce the necessity of insulin secretion and therefore prevents insulin resistance

Question 14

What is glucose uptake like at rest, early and late exercise

Answer 14

Rest - extra glucose is converted into glycogen - small amount

Early - facilitated influx of glucose but glycogen is broken down so there is less of a demand

Late - lots of glucose influx to replenish glycogen stores

Question 15

What does endurance training increase what

What does this do

Answer 15

Muscle glycogen storage and glut4 content

Which improves blood glucose control