LEC: Local Anesthesia Flashcards
How to local anesthetics work/mechanism of action?
Interferes with the movement of sodium ions across neronal cell membranes
What is local anesthesia?
Odd of pain sensation and midnent in an area of the body due to blockage of nerve conduction
What are four esters?
Cocaine procain chlorprocain and propraracain
What are three amides?
Lidocaine, mepivacain, bupivacaine
What are two local anesthetics?
Esters and amides
What local anesthesia only lasts a few minutes and is topical?
Esters
What local anesthetic is used for small animals?
Amides
How can you administer amides? 3
SC
sometimes IM
rarely IV
How are amides eliminated?
Metabolized by the liver
Out of the three amides, which one is the shortest lasting?
Lidocaine
How long does lidocaine last?
1 1/2 - 2 hours
How much more potent is lidocaine compared to procain?
2x
What is the most popular amide?
Lidocaine
Why is epinephrine not added to lidocaine for dysarrythmia?
Because epinephrine will increase the heart rate
How long does mepivacain last?
1.5-3 hours
How muchc more potent is mepivacain compared to procain?
2.5x
What is mepivacain a best quality?
Less irritating to tissue when SC or IM
How long does bupivacaine last?
4-6 hours
How much more potent is mepivacain than procain?
8-10x
When is bupivacaine used?
When they need a local anesthetic to last a while
What are five adverse effects of local anesthesia?
Tissue irritation Allergic reaction Nerve trauma Respiratory paralysis and sympathetic block with epidural Systemic toxicity
What are three specific techniques for administrating local anesthesia?
Topical application
Localized infiltration
Regional injection
What nerves will be blocked with an L line block?
T13 and L1
What nerves will be blocked with an inverse line block?
T13, L1, and L2