lec5 : blood groups Flashcards
(16 cards)
any substance recognized by the body as
foreign
Antigen
Antigen on the surface of RBCs
agglutinogens
the most important and best known agglutinogens are the ……………
A and B agglutinogens
Antibodies against red cell agglutinogens are called
………………. and they are present in ……………..
agglutinins
plasma
Frequency in population of BG A ……….
41%
Frequency in population of BG B ……….
10 %
Frequency in population of BG AB ……….
4 %
Frequency in population of BG O ……….
45 %
When A or B antigen meet its corresponding antibody, ……………………………………………………
agglutination reaction occurs.
In agglutination reaction , RBC …………………………….
clump and stick to each other then hemolyse
WHY The agglutinins attach themselves to the RBCs?
Because agglutinins have many binding sites, a single
agglutinin can attach to different red cells at the same time
“Rh‐positive” found in…………………… of population.
85-90%
The population are divided according to presence of ………………… into Rh‐positive and Rh‐negative
D‐Antigen
Hemolytic disease of the New‐born
Erythroblastosis Fetalis
t is a condition due to Rh‐incompatibility between mother and fetus blood
Erythroblastosis Fetalis
to prevent sensitization of a Rh‐negative mother,
she is given a single dose of …………………………… in the first……………… after
delivery starting from ………….. delivery
anti‐Rh antibodies (Anti‐D immune globulin)
48 hours
first