Lect 5 Oral cavity Flashcards

(54 cards)

1
Q

oral cavity divisions

A

vestibule-space bw lips, cheeks and teeth

oral cavity proper - hard and soft palate, tongue and floor of mouth, entrance to oropharynx

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2
Q

Functions

A

porpulsion
initiation of digestion
protection
sensation (taste buds, reflexes, temp, touch)
secretion - saliva (major and minor glands), sebaceous glands secrete sebum

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3
Q

Protection of oral cavity

A

oral mucosa separates and protects deeper tissues
prevents microorganisms from gaining access to underlying tissues
Tonsils: immunological protection
Forms impermeable barrier (except floor of mouth)
Permeability barrier consists of lipids derived from the membrane – coating granules released into the intercellular space

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4
Q

order of layers of oral mucosa

A

Epithelium -> CT (both make up lamina propria) -> submucosa -> bone

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5
Q

organization of oral mucoperioseum

A

epithelium ->lamina propria -> periosteum->bone

gingiva and parts of hard palate, forms a firm inelastic attachement

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6
Q

organization of oral mucosa

A
2 main components - epithelium and CT
not all regions have a submucosa layer 
**no muscularis mucosae layer in the oral cavity
structural variations based on location
3 types
Masticatory, lining, specialized
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7
Q

masticatory mucosa

A

stratified squamous keratinized or parakeratinized epithelium
lamina propria
covers gingiva, hard palate
injections are painful, infection spreads slowly

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8
Q

parakeratinized epithelium

A

similar to keratinized except that superficial cells do not lose nuclei, cytoplasm does not stain as intensely with eosin

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9
Q

Lining mucosa

A

stratified squamous non keratinized epithelium
covers inner surface of lips, cheeks, soft palate, inferior surface of tongue, floor of the mouth
CT have elastic fibers that control extensibility
Permeability- impermeable except floor of mouth
sublingual medications are readily absorb

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10
Q

sprecialized mucosa

A

dorsal surface of the tongue - taste buds

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11
Q

lips

A

guard passage to oral cavity
3 parts:
cutaneous, vermillion border, oral mucosa

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12
Q

cutaneous

A

outer portion of thin skin (SSKE) with hair follicles and glands

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13
Q

vermillion border

A

dry, red portion covered with thin keratinized skin - NO sweat glands or hair follicles

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14
Q

oral mucosa

A

inner mucous membrane portion, thick lining epithelium (SSNKE)

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15
Q

Alveolar mucosa

A

mucous membrane of the lip reflects back onto the alveolar bone
termed vestibular fold (thin lining mucosa)
-mucosa immediately surrounding an erupted tooth is the gingiva
-mucosa: masticatory

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16
Q

Differences of gingiva and labial mucosa

A

gingiva is tightly bound to bone by dense fibrous CT

lip epithelium is supported by much looser CT

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17
Q

Gingiva

A

oral mucosa surrounding erupted tooth

  • gingiva mucosa - faces oral cavity
  • junctional epithelium (attachment epithelium): faces tooth - adheres firmly to the enamel/cementum via hemidesmosomes
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18
Q

Dentogingival junction

A

potential weakness in otherwise continuous epithelial lining: potential risk of inflammation
Basal cells rest on a typical basal lamina that interfaces with CT
-most superficial cells provide attachment of the gingiva to the tooth surface by means of epithelial attachment
-consists of an inner basal lamina that adheres to the tooth surface, cells are attached by hemidesmosomes

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19
Q

Clinical significance of oral mucosa

A

CT fibrosis
epithelium - can be affected by a number of pathological conditions
-squamous cell carcinoma
-melanoma
-leukoplakia (white patch of keratinized or parakeratinized epithelium)

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20
Q

Tongue

A

Striated muscle lined with mucous membrane

muscle fibers arranged in three planes results in precise movements

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21
Q

dorsal surface of tongue

A

specialized epithelium
divided into anterior two thirds (body), posterior one third (root)
mucosal irregularities/elevations called lingual papilla (foliate, fungiform, filiform, valate papillae)

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22
Q

ventral surface

A

lining mucosa

23
Q

Four types of papillae

A

Filiform, foliate, fungiform, circumvallate/vallate

24
Q

Filiform papillae

A

smallest and most numerous
taste buds not associated w. this epithelium
structure: conical projections of CT covered with highly keratinizes SS epithelium
function: forms tough abrasive surface for a mechanical role
location: distributed across entire dorsal surface of the tonge

25
foliate papillae
deep, mucosal clefts on lateral aspect of the tongue | contain many taste buds in younger individuals, poorly developed in adults
26
fungiform papillae
mushroom shaped projections scattered on dorsal surface more numerous at tip of tongue numerous taste buds
27
Circumvallate papilla
large dome shaped structures located just anterior to sulcus terminalis 8-12 in human tongue surrounded by a moat like invagination lined with multiple taste buds von ebner's glands produce a purely serous product into the moat (fluid washes away old taste stimulation to enhance taste of new stimuli)
28
Taste buds
specialized clusters of epithelial cells (50-90 fusiform shaped cells - narrow apical ends converge to form a taste pore 3 types: neuroepithelial cell (sensory), supporting cells, basal cells
29
neuroepithelial cells
aka sensory cells microvilli that have receptor to interact with tastant, extends from apical cell through the taste pore form synapse with afferent sensory neuron cell turnover 7-10 days
30
supporting cell
microvilli on apical aspect | do not synapse with nerve cells
31
basal cells
small cells | stem cell for both neuroepithelial and supporting cell
32
salivary glands and saliva
fluid of the oral cavity=saliva forms first barrier against infection large volumes produced daily, varies per individual majority produced by 3 paired major salivary glands minor salivary glands contribute to total amount of saliva, all are mixed mucous and serous glands EXCEPT von Ebner's glands
33
Salivary functions
``` moisten oral mucosa moisten food - aid in swallowing stimulates taste buds buffers contents of oral cavity tissue repair digestion (amylase) Tooth development and maintenance ```
34
Salivary gland structure
arises from developing oral cavity epithelium consists of secretory component and a duct component lobes of gland subdivided into lobules by CT
35
Acini
blind ended duct that is composed of secretory cells 3 types serous, mucous, mixed
36
serous acini
only serous cells, protein secretions stored in zymogen granules in the apical aspect of the cell
37
mucous acini
cells contain mucinogen granules
38
mixed acini
both serous and mucous cells, mucous cells appear to have a cap of serous cells called serous demilunes
39
myoepithelial cells
contractile cells w/ numerous processes location: between the basal plasma membrane of acinar secretory cells and the basal lamina of the epithelium (also in the proximal duct system) function: aids in transporting the secretory product to the duct portion of the salivon
40
Salivary ducts
intercalated - low cuboidal epi cells striated - larger cuboidal cells becoming columnar - infoldings of the basal plasma membrane involved in reabsorption of electrolytes form 'striations' in histological sections
41
Excretory ducts
larger ducts and ultimately connect w/ oral cavity travel in CT of gland and form the principle duct portion epithelium changes as it blends with the epithelium of the oral cavity from simple cuboidal/columnar to pseudo stratified columnar to stratified squamous
42
Duct component summary
mucous/mixed/serous cells -> small intralobular intercalated duct -> striated duct -> interlobular duct -> statified columnar epi -> main duct
43
3 major salivary glands
Parotid, submandibular, sublingual
44
Parotid glands
completely serous with a well developed duct system enclosed in a tough CT capsule fatty tissue allows flexibility
45
submandibular glands
mixed, predominant serous acini | duct runs forward to beneath the frenulum of the tongue
46
sublingual glands
``` mostly mucus secreting glands (serous demilunes present, but rarely serous acini) multiple ducts (very small) empty to to submandibular duct or floor of the mouth ```
47
saliva production
net reabsorption of sodium and chloride produce hypotonic, alkaline saliva. rich in potassium and bicarbonate
48
teeth
32 permanent 20 deciduous begin digestive process three hard tissue types: enamel dentin cementum
49
enamel
avascular acellular, nonvital 96% inorganic material in form of hydroxyapatite hardest calcified matrix in body, rods and interrod formation derived from ectoderm ameloblasts
50
dentin
less mineralized than enamel odontoblasts works with pulp for repair
51
pulp cavity
richly vascularized, soft CT
52
cementum
covers root of tooth, locked to dentin mineralized similar to bone avascular cementoblasts derived from ectomesenchyme
53
Periodontal ligament
located bw cementum and alveolar bone principal fiber groups of type 1 collage, specifically arranged to absorb and conteract masticatory forces Ends of principal fibers are embedded in alveous and cementum as Sharpeys fibers richly vascularized
54
PDL functions
tooth attachment tooth support- adjust to stress and movement, avoids direct transmission onto bone which would cause resorption proprioception Difference from other ligaments- highly vascularized, highly cellular, lots of nerves collagen fibers have high turnover rate: poor nutrition causes atrophy and teeth can become loose in their sockets