Flashcards in Lecture 1 Deck (4)
How do intra and extracellular pathogens establish infection?
The pathogen attachment and entry into host, extracellular pathogens will then replicate and spread to cause either local and systemic infections
Intracellular pathogens will enter into cells and replicate and then go on to spread infection
What are the barriers to infections from pathogens?
Lysozyme in tears, mucus and cilia in the bronchi, acids and rapid pH change in the gut, commensals in the gut, skin fatty acids and commensals
What is the difference between PAMPs and antigens?
PAMPS are general structures recognized by the innate immune system
Antigens are the highly specific structures recognized by the adaptive immune system