Lecture 1: Nature of Drugs & Drug Development Flashcards
(92 cards)
Pharmacology definition
the study of substances that interact with living systems through chemical process, especially by binding to regulatory molecules and improving or impressing normal function
define medical pharmacology
the science of substances uses to prevent, diagnose and treat disease
define toxicology
the branch of pharmacology that deal with undesirable effects of chemicals on living things
pharmacodynamics
describes the action of the drug on the body (physical, molecular, and biochemical level)
pharmacokinetics
investigates the effects of the body drugs (ADME)
drug
any substance that causes alteration in cellular / biopic effect
therapeutic agent
a drug used to treat a medical condition or disease
prophylactic agent
a drug used to prevent a medical condition or disease
pharmacy
the profession of preparing, compounding, and dispensing chemicals for medical use
pharmacogenetics/genomics
examines the role of genetics on different drug responses
medicinal chemistry
design and synthesis of drug compounds
pharmaceutics
design and synthesis of drug formulations (ex: extended release)
there is evidence of natural remedies in the earliest writings of ancient ___, ___ , and ___
Egypt, china, greece
what was the start of early drug development in the 1800s
isolation of natural products
morphine is purified from ___
opium found in products
who was credited with developing early experimental physiology and pharmacology?
Francois magendie and Claude Bernard
the ingredients were not required to be disclosed until the ___ act in the US in __ and the ____ act in Canada in __
pure food and drug act, 1906; Food and Drugs 1920
what is the drug regulatory body in the US
FDA
what is the drug regulatory body in Canada
health Canada
what is the drug regulatory body in Europe?
European Medicines Act
section 9(1) of the health Canada food & drugs act prohibits advertising which is __, __, __, or is likely to create ___ impression regarding its character, value, quantity, composition, merit or safety
false, misleading, deceptive, erroneous
section 9(1) of the health food & drug act prohibits messages which emphasize only __ without including information on __
benefits; safety
section C 01. 044 of the Canada Food and Drug regulations prohibits consumer-directed ___ advertising beyond what 3 things? No reference can be made to its therapeutic ___ or __
Rx; Name, quality and price; use or benefits
health Canada prohibits the ____ of drugs which have not been authorized for sale by Health Canada
advertising