lecture 1: neurology Flashcards

1
Q

central nervous system is considered a ____

A

upper motor neuron disorder

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2
Q

what are 2 examples of my or neuron disorders in the peripheral nervous system (UMN/LMN)

A

• Amyotrophic Lateral Sclerosis (Lou Gherig’s disease)*
• Polio/post polio syndrome*

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3
Q

what are 3 examples of peripheral nerve disorders in the peripheral nervous system

A

• Radiculopathies
• Plexopathies
• Polyneuropathy

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4
Q

• Myasthenia gravis
• Lambert Eaton’s myasthenic syndrome
• Botulism

these are all examples of what kind of disorders

A

neuromuscular junction

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5
Q

what is capgras delusion

A

recurrent belief that a person has been replaced by an imposter

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6
Q

capgras delusion , stiffperson syndrome , and prosopagnosia are examples of what

A

fascinomas

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7
Q

capgras delusion is reported with lesions in the ___ hemisphere

A

right

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8
Q

what syndrome is diffuse stiffness without weakness or numbness and is an autoimmune disorder

A

stiffperson syndrome

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9
Q

define prosopagnosia and what side hemispheric lesion is it

A

inability to recognize faces of familiar people

right side

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10
Q

good ___ is essential tp the diagnosis

A

history

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11
Q

• Disordered mentation, attention, memory, behavior
• Language and communication disturbances
• Excessive daytime sleepiness, insomnia, fatigue
• Visual disturbances (vision loss, diplopia)
• Weakness, numbness, other sensory alterations, balance
problems
• Sphincter disturbances (urinary or fecal incontinence, inability
to void)
• Erectile or ejaculatory dysfunction
• Sudden (paroxysmal) behavioral changes (seizures, loss of
consciousness)

these are all complaints of what

A

neurologic

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12
Q

what are the 8 things that weakness could mean

A

– Fatigue
– Apathy
– Pain
– Decreased sensation
– Imbalance
– Incoordination
– Drowsiness
– Loss of muscle strength

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13
Q

what are the 7 things to check for neurologic exam

A

I. Mental Status & Language
II. Cranial Nerves
III. Motor
IV. Sensation
V. Reflexes
VI. Coordination
VII.Gait

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14
Q

what are the 4 levels of consciousness

A

alert

lethargy

stupor

coma

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15
Q

what level of consciousness are you awake and interactive

A

alert

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16
Q

what level of consciousness will the pt appear asleep but may be aroused with stimulation to interact with environment

A

lethargy

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17
Q

what level of consciousness will the pt arouse briefly to vigorous stimuli but not to the point of being interactive

A

stupor

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18
Q

what level of consciousness is the pt unresponsive to external stimuli

A

coma

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19
Q

what is apraxia

A

inability to carry out a motor act int he absent of weakness or ataxia

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20
Q

what is dysarthia and what kind of disorder is it and ehat does it affect

A

slurred speech

motor disorder affecting the muscles of articulation

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21
Q

what is aphasia

A

impairment of lang production or comprehensions

  • broca’s area
  • wernickes area
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22
Q

whar are the 6 components of language

A

spontaneous speech

naming

comprehension

repetition

reading

writing

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23
Q

what is the path of language in the brain

A
  1. heschl’s gyrus , primary auditory cortex
  2. wernickes area , superior temporal gyrus
  3. arcuate fasciculus
  4. broca’s area , left inferior frontal
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24
Q

what links written words with language

A

angular gyrus

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25
what is **anosmia** mean
loss of smell
26
what is **dysguesia**
altered taste
27
what are common path for cranial number 1 (olfactory nerve) sumptomatic and asymptomatic
symp: post viral , head trauma asymptomatic: alzheimer’s , parkinson’s
28
what CN deals with – Visual acuity – Visual fields – Ophthalmoscopy – Pupillary reactivity (afferent limb) – Color perception
cn II: optic
29
what mm goes with CN IV: trochlear N
superior oblique mm
30
what mm does the motion for CN VI: abducens N
lateral rectus MM
31
what exam do you do for CN III, IV and VI
extraocular movements , ptosis
32
what mm do the motion for CN III: oculomotor
superior rectus inferior rectus medial rectus inferior oblique
33
when you are doing the swinging flashlight test what is the direct response and consensual response
the direct response is shine light into pupil and look for constriction consensual response is look for opposite pupil constriction
34
if you do the swinging flash light test and there is no direct response what is the problem
problem with ipsilateral optic never
35
if you do the swinging flashlight test and there is no consensual response what can be the 3 problems
problem with opposite optic nerve , ipsilaterla parasympathetic of CN 3 or pupillary constrictor mm
36
what CN is – Muscles of mastication (chewing) – sensation of the face, conjunctiva, sinuses
CN V: trigeminal nerver
37
what is the exam for CN V: trigeminal
corneal reflex strength of jaw facial sensation
38
what 2 CN does the corneal reflex test and what are u doing and looking for
CN V and VII touch cornea gently with cotton swab and look for eye lid blinking
39
what CN is this – Muscles of facial expression, stapedius – Lacrimal glands (tearing) – Taste of anterior 2/3 of tongue
CN VII: facial
40
what is the exam for CN VII: facial
show teeth , wrinkle forehead, close eyes tight
41
if there is a central lesion for CN VII what does that mean
lower half of face weak on the contralateral side (stroke) ## Footnote if there is a right sided lesion then the left half od the lower face will be weak bc it crosses
42
if there is a peripheral lesion for CN VII: facial what does tha mean
entire half of face weak on the ipsilateral side bell’s palsy
43
what is the exam for CN VIII: vestibulochoclear nerve
hearing to finger rubs or tuning fork eye movements , nusyagmus head thrust dix hall pike
44
what cn is this – Sensation/taste from posterior 1/3 tongue, back of the throat – Motor nerve elevates pharynx, contributes to gag – Parasympathetics to parotid
CN XI: glossopharyneal nerve
45
what CN is this – Motor nerve innervating muscles of pharynx, larynx, tongue, smooth muscles – Major autonomic nerve - parasympathetic efferent
CN X: vagus nerve
46
what is the exams for CN XI and X
palatial elevation gag reflex taste swallowing assessment of speech
47
what 2 mm does the CN XI: accessory n inn
SCM and traps
48
what CN INN the tongue MM
CN XII: hypoglossal n
49
what are the 3 different tones
flaccidity rigidity spasticity
50
what is flaccidity define as
little resistance to passive movement
51
what tone is steady muscular tension that is equal in degree in opposing mm groups
rigidity
52
what tone is sustained increase in tension of a mm when it is passively lengthened
spasticity
53
which tone is speed dependent
spasticity
54
what brain strucutre has to do with rigidity
BG
55
atrophy, pseudohypertrophy these are consider what in the motor exam
bulk
56
what 2 things do you check in the motor exam
bulk and tone
57
what are the 5 upper motor neuron signs
- stiffness , spasticity - weakness in pyramidal pattern ( flexor strong in UE and extensors stronger in LE ) - hyperreflexia -pathological reflexes - babinskis
58
what are the 4 lower motor neuron sign
-•Weakness, muscle atrophy, fasciculations, cramps. •NO SENSORY INVOLVEMENT •NO PAIN •Hypoactive reflexes
59
what grade of power is partial arc of movement with gravity eliminated
2
60
what grade of power is full arc against gravity and some added resistance
4
61
what number is it if the reflex is normla
2+
62
what do you rate a clonus reflex
4+
63
what is a Series of rhythmic involuntary muscle contractions induced by sudden passive stretching of a muscle
clonus (UMN lesion)
64
is hoffmann sign UMN or LMN and what finger do you do it on
UMN and middle
65
what is the babinski sign
extensor plantar response
66
when is the babinski sing abnormal
when the toes goes up (except in babies)
67
what tract is pain and temperature
lateral spinpthalamic tract
68
what tract is light touch
ventral spiniothalamic tract
69
what tract is vibration and proprioception
DCML
70
what part of the neurologic exam do you – Screen for distal/proximal gradient, asymmetry, dermatomes
V. sensation
71
what is one of the more earliest signs of dorsal column disease
romberg sign
72
when sit he romberg sign positive
when pt is able to stand with his feet together while his eyes are open but sways or falls when they are closed
73
when is the romberg sign included during the neurologic exam
sensory or coordination exam
74
when during the neurologic exam do you test the function of the cerebellum, basal ganglia, and related connections.
VI. coordination exam
75
disorders of the coordination exam manifest as what 5 things
imbalance incoordination ataxia dusdiadochokinesia abnormal movements
76
what 2 coordination test assess for dysmetria and intention tremor
finger nose finger test and heel to shin test
77
what does rapid alternation movements test for
dysdiadochokinesia
78
define station
attitude or manner of standing , including posture
79
what does fiat assess
width of the base , arm swing , pelvis rotation , height of step and symmetry
80
MRI, CT, myelography, angiography, perfusion, DAT are all examples of what
neuro imaging
81
electroencephalography (EEG), electromyography (EMG), nerve conduction studies, evoked potentials these are examples of what
neurophysiology
82
– Inflammatory and infectious conditions, including meningitis, encephalitis, multiple sclerosis – Subarachnoid hemorrhage – Pseudotumor cerebri (idiopathic intracranial hypertension): high opening pressure – Cancer involving meninges what is a diagnosis of these things
lumbar puncture
83
lumbar puncture inject what medications
chemotherapy , anesthesia
84
what levels of the spinal cord does the lumbar puncture go in at and into what space
L4/L5 epidural
85
what is normla measure pressure for lumbar puncture ____ mm H2O
80-200
86
what are some complications for lumbar puncture
post LP HA bleeding infection back pain
87
what are 5 advantages of computed tomography
– Emergency diagnosis of acute conditions (stroke, trauma). Blood easily seen. – Quick and readily available – Only option for those with contraindications to MRI – Visualization of bone (skull) – High resolution of vascular structures
88
what are disadvantages of computed tomography
radiation exposure and poor visualization of BS
89
what is hyper dense on a CT
calcium and bone
90
what is hypodense (dark) on CT
CSF, fat
91
is white matter or grey matter darker on CT
white
92
is blood hyper dense or hypodense on CT
hyper dense
93
on a CT , stroke , edema , fluid and air are ____
hypodense
94
what are the 3 advantages of MRI
no radiation exposure much higher resolution unmarred by bony artifact
95
what are 3 disadvantages of MRI
some contraindications (pacemaker) can’t assess bone long acquisition time
96
what is the test of choice for imaging most central nervous system disease/lesions
MRI
97
what choice of imaging would you do for these … infarcts, hemorrhages, vascular malformations, aneurysms, tumors, degenerative disorders, contusions, demyelination (MS), epilepsy, infections
MIR
98
can an MRI be done with or without contrast material (gadolinium)
yes
99
MRI: delusion weighted imaging is ___ in acute stroke
bright
100
what is an injection of 5-25 mL of radiopaque dye into **subarachnoid space** via lumbar puncture.
myelography
101
myelography is combined with what to allow for visualization of subarachnoid space
CT scanning
102
what are the 4 things that myelography evaluates for
spinal stenosis , cord arteriovenous malformation , tumor and abscess
103
what do you usually do instead of a myelography
MIR
104
what is injection of dye into cranial arteries (via catheterization from femoral artery)
conventional angiography
105
what can you visualize with a conventional angiography
occlusion , dissections , primary angiitis , aneurysms , vascular malformations
106
conventional angiography is. an intra arterial injection of ___
thrombolytic
107
what is interventional for conventional angiography
clot removal , stenting , angioplasty , coils and glue
108
what measure brain electrical activity thru scale electrodes
EEG
109
what does an EEG evaluate for
seizures , brain death , encephalopathy , dementia , coma
110
what is a Recording of electrical activity in central sensory pathways produced by visual (VEP), auditory (BAEP), or sensory (SSEP) stimulation
evoked potential
111
what does VEP evoked potentials mean
alternation checkerboard pattern
112
what is BAEP (auditory) evoked potientials mean
auditory clicks thru earphones
113
what does SSEP ( sensory) evoked potential mean
electrical stimuli applied to peripheral nerves
114
what do you use for Diseases of muscle, nerve, neuromuscular junction
EMG (electromyography) and NCV ( nerve conduction velocities)
115
what is an Insertion of a small needle into individual muscles and recording of motor unit potentials at rest and with activity
electropgyogrpahy
116
what is an Electrical stimulation over nerves with recording of sensory and motor nerve potentials and velocities
nerve conduction velocities
117
what will an axonal neuropathic show for an eMG and NCV
decreased amplitudes on NCV , abnormal spontaneous activity on EMG
118
what will a demyelinating neuropathies show on a EMG and NCV
slowed condution
119
what will a myopathies show on an EMG and NCV
normal NCV , small duration , low amplitude potentials
120
what does myasthenia gravis show on an EMG and NCV
abnormalities on repetitive nerve stimulation
121
what does this describe – Increased tone – Hyperreflexia – No atrophy
UMN
122
what does this describe – Decreased/normal tone – Hyporeflexia – Atrophy
LMN