Lecture 10: Lumbar Plexus and Pain Flashcards

1
Q

What is the excitatory hormone of the somatic NS, are there ganglia, and what are the axons like?

A
  • Ach
  • No ganglia in this pathway
  • Axons are thick and myelinated
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2
Q

What is the NT used by pre-ganglionic cell bodies in the sympathetics; how about post-ganglionic?

A

Pre-ganglionic = Ach

Post-ganglionic = NE

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3
Q

What are the 2 components of the sympathetic trunk?

A

Paravertebral ganglion + Interganglionic connections

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4
Q

What are the 3 cervical ganglion?

A
  • Superior
  • Middle
  • inferior
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5
Q

What ganglion is formed by the fusion of the inferior cervical ganglion w/ the ganglion of T1?

A
  • Stellate ganglion
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6
Q

What are the 4 options for pre-synaptic fibers entering the sympathetic trunk?

A

1) Ascend
2) Descend
3) Synapse at same level
4) Traverse the trunk w/o synapsing and become part of an abdominopelvic splanchnic nerve or for innervation of the suprarenals

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7
Q

What are gray rami communicans; how many spinal nerves?

A
  • All 31 spinal nerves
  • Arise as lateral branches
  • Carry post-synaptic fibers to body wall and limbs for distribution via spinal nerves
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8
Q

What are the cephalic arterial rami?

A
  • Go to periarterial plexuses of carotid arteries
  • Arise from cervical ganglia
  • Post-synaptic fibers to head for distribution via periarterial plexuses
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9
Q

What are the 3 primary effects of the parietal branches of sympathetic trunks?

A

1) Vasomotion
2) Sudomotion - sweating
3) Pilomotion - erector pilae m. = goosebumps

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10
Q

What is the primary contribution to the celiac ganglion?

A

Greater splanchnic n

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11
Q

What is the primary contribution to the aorticorenal ganglion?

A

Predominantly lesser splanchnic

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12
Q

What is the primary contribution to the SMG?

A

Contributions from all

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13
Q

What is the primary contribution to the IMG?

A

Primarily lumbar

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14
Q

How do abdominopelvic splanchnic nerves enter the diaphragm?

A

They pierce the muscle

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15
Q

Which fiber type do the cardiopulmonary splanchnic nerves convey and what kind of ganglia do they synapse in?

A
  • Convey POST-synaptic fibers to thoracic viscera

- Synapse in PARA-vertebral ganglia

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16
Q

Which fiber type do the abdominopelvic splanchnic nerves convey and what kind of ganglia do they synapse in?

A
  • Convey PRE-synaptic fibers

- Synapse in PRE-vertebral ganglia

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17
Q

Do the paravertebral ganglia of sympathetic trunks distribute fibers to the abdominopelvic viscera?

A

NO, everywhere else

*Pre-vertebral ganglia of para-aortic plexus distribute to abdominopelvic viscera

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18
Q

Why is innervation of the suprarenal glands an exception?

A

Pre-synaptic fibers to the suprarenals will pass through the pre-vertebral ganglia WITHOUT synapsing. The synapse occurs directly on the secretory cells of the medulla which act as postsynaptic neurons.

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19
Q

How are the pre-synaptic neurons of the sympathetics and parasympathetics different?

A

Sympathetics = short

Parasympathetics = long

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20
Q

What is the dominant outflow of the parasympathetic presynaptic neurons; where does it extend to?

A

Cranial outflow is dominant (extends to left colic flexure)

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21
Q

Where are the parasympathetic postsynaptic neurons located in the trunk?

A
  • Widely spread and irregularly spaced
  • Located in or on effector (intrinsic/enteric ganglia)
  • Found in the Musculosa Externa
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22
Q

What are the parasympathetic postsynaptic neurons in the head?

A

1) Ciliary
2) Otic
3) Pterygopalantine
4) Submandibular

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23
Q

Do the parasympathetics go to body walls or limbs; are they components of spinal nerves?

A
  • Do NOT go to body walls or limbs, except erectile tissue of external genitalia
  • Never components of spinal nerves of their peripheral branches, except for initial parts of S2-S4
24
Q

What is the left colic (splenic) flexure a landmark for?

A

Where cranial outflow (i.e., Vagus n.) stops and the Sacral outflow (S2-S4) starts

25
What is the effect of the sympathetic NS on the BV's of the GI, sphincters, peristalsis, and suprarenal glands?
- Constricts BV's of skin and GI tract - Decreases peristalsis of gut, constricts sphincters - Stimulates suprarenal glands to release adrenaline
26
Where does the sympathetic NS not produce vasoconstriction?
The heart and muscles
27
What is the effect of the parasympathetic NS on gut peristalsis, sphincters, the rectum, and bladder?
- Increases peristalsis - Inhibits sphincters - Stimulates contraction of bladder and rectum
28
Which part of the autonomics is the primary stimulator of the GI tract?
Parasympathetic *Is active in elimination (defecation and urination)
29
Where are the cell bodies for visceral afferent fibers?
Dorsal root ganglion
30
Normal homeostatic reflexes (physiologic receptors) travel w/ which part of the autonomics?
The parasympathetics
31
Pain travels with which part of the autonomics and what is the transition point?
The sympathetics until the pelvic pain line, then switches to parasympathetics
32
Where is the pelvic pain line?
Middle of the sigmoid colon
33
Differentiate acute, chronic, and subacute abdominal pain?
Acute = <3 days Chronic = >3 weeks Subacute = 3 days - 3 weeks
34
Which type of pain is well localized, which type of pain is not?
Visceral = not well localized Parietal (somatic) = well localized
35
Parietal pain is caused by?
Irritation of fibers that innervate the parietal peitoneum (i.e somatic nerves - thoracoabdominals)
36
How can parietal pain be localized?
To the dermatome superficial to the site of the pain stimulus
37
How can visceral pain be localized?
By the sensory cortex to an approximate spinal cord level determined by the embryologic origin of the organ involved
38
Where is pain produced from: foregut, midgut, and hindgut organs?
``` Foregut = Epigastrium Midgut = Periumbilical Hindgut = Suprapubic/Hypogastric region ```
39
What pathologies will cause pain in the umbilical region?
- Appendicitis (early) - Mesenteric adenitis - Meckel's diverticulitis - Lymphomas
40
What pathologies will cause pain in the right inguinal region?
- Appendicitis (late) - Chron's Disease - Cecum obstruction - Ovarian Cyst - Ectopic pregnancy
41
Which pathologies can lead to pain in the shoulder; how?
- Liver - Gallbladder - Duodenum *Irritation of the diaphragm
42
Retroperitoneal pain is commonly felt where; which structures cause this pain?
- Felt in the back | - Pancreas, kidneys, aorta
43
What is Colicky pain; causes?
- Intermittent cramp-like pain | - Bowel obstructions/adhesions, stone in ureter, stone in neck of gallbladder
44
If the patient has epigastric pain that is worse after eating what is the underlying pathology; how about 2-5 hours after eating?
- Immediate = stomach | - Delayed (2-5 hrs) = Duodenum
45
Anytime something ruptures or is extremely inflamed what kind of pain is likely to follow?
Generalized or localized peritonitis
46
If patient has midgut visceral colicky pain, vomiting, NO flatus or bowel action, and increased bowel sounds, what is the likely pathology?
Adhesive small bowel obstruction
47
Pt has a sudden onset of very severe colicky pain in the flank region, severe back pain, tender renal angle, possible hematuria, what is likely pathology?
Passage of a kidney stone
48
Pt is older w/ sudden weight loss, hindgut visceral colicky pain, no flatus/feces, increased bowel sounds, a mass in LLQ, what is the pathology?
Obstructing cancer of descending colon
49
Women of childbearing age, missed her last menstrual period, sudden onset of severe hypogastrium pain radiating to sacral area, localized suprapubic peritonitis; what is likely pathology?
Ruptured ectopic pregnancy
50
Pt is an elderly male w/ hx of atherosclerotic disease (HTN or cardiac) w/ a sudden onset of severe back pale, appears pale and shocked, is HYPOtensive and has a palpable impulse in epigastrium; what is the likely dx?
Leaking aortic aneurysm
51
Pain from which organs will be traveling with greater splanchnic afferent nerve fibers?
- Liver - Stomach - Spleen - Supra-adrenals
52
Pain at the ileocecal junction, cecum, appendix, ascending or transverse colon will travel with which afferent nerve fibers?
Lesser splanchnics
53
Pain in the duodenum, ileum, and jejunum will be carried w/ which afferent nerve fibers?
Greater and Lesser splanchnic
54
Pain in the descending colon will be carried w/ which afferent nerve fibers?
Least and lumbar splanchnic
55
Pain in the kidneys will be carried with which afferent nerve fibers?
Lesser, least, and lumbar splanchnics
56
Which nerve fibers will transmit pain from the sigmoid colon and rectum?
Pelvic splanchnic
57
Which areas will cause pain initially in the suprapubic/hypogastric area?
- Hindgut organs (most of colon, including 1/2 sigmoid) | - Intraperitoneal portions of the genitourinary tract