Lecture 10: Overview of Circulation Flashcards

1
Q

What is systolic arterial pressure in the systemic circulation?

A

120 mm Hg

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2
Q

What is the diastolic arterial pressure in the systemic circulation?

A

80 mm Hg

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3
Q

What is the pulmonary artery systolic pressure?

A

25 mm Hg

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4
Q

What is the pulmonary diastolic pressure?

A

8 mm Hg

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5
Q

What are the functional parts of the arteries?

A
arteries
arterioles
capillaries
venules 
veins
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6
Q

What do the arteries do in circulation

A

transport under high pressure

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7
Q

What do the arterioles do in circulation?

A

control conduits

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8
Q

What do capillaries do in circulation?

A

exchange between blood and extracellular fluid

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9
Q

What percent of blood volume is in the systemic circulation?

A

84%

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10
Q

What percent of blood is in the veins?

A

64%

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11
Q

What percent of blood is in the arteries?

A

13%

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12
Q

What percent of blood is in the systemic arterioles and capillaries?

A

7%

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13
Q

What percent of blood is in the heart and lungs?

A

16%

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14
Q

What is the equation for velocity of blood flow?

A

V= F/A

F= volume of blood flow
A= cross sectional area
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15
Q

Rate of blood flow to each tissue of the body is almost always precisely controlled in relation to what?

A

to the tissue need

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16
Q

The cardiac output is controlled mainly by _______

A

sum of all the local tissue flows

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17
Q

Arterial pressure regulation is generally independent of either ________ or _________

A

local blood flow

cardiac output control

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18
Q

What is pressure gradient?

A

pressure difference between the two ends of a vessel

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19
Q

What is resistance?

A

impediment to blood flow through the vessel

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20
Q

Ohm’s law

A

F= change in pressure/ resistance

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21
Q

What is the overall blood flow of an adult at rest?

A

5000 ml/min

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22
Q

Laminar blood flow = _________ flow

A

streamline

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23
Q

In laminar flow, the velocity of fluid flowing in center is _______ than that of fluid flowing towards outer edge

A

greater

24
Q

what is turbulent flow?

A

nonlayered flow

25
Q

Turbulent flow creates _____ and produces more _____ than laminar flow

A

murmurs; resistance

26
Q

When does turbulent flow occur?

A

when flow is too great
when blood passes an obstruction with the vessel
when blood has to make a sharp turn
when flood passes over a rough surface

27
Q

Tendency for turbulent flow increases in ______ proportion to velocity of blood flow

A

direct

28
Q

Tendency for turbulent flow increases in ______ proportion to diameter of the vessel

A

direct

29
Q

Tendency for turbulent flow increases in ______ proportion to density of the blood

A

direct

30
Q

Tendency for turbulent flow increases in ______ proportion to viscosity

A

inverse

31
Q

Laminar flow equation

A

Re= (vdp)/ n

v= mean velocity of blood flow
d= vessel diameter
p= density
n= viscosity
32
Q

What is Re?

A

Reynolds number, the measure for the tendency for turbulence to occur

33
Q

When Re rises above 200-400, turbulent flow will occur in _____ regions of a vessel

A

some

34
Q

When Re rises above 2000, turbulence will even occur in _____ vessels

A

straight

35
Q

What is blood pressure?

A

the force exerted by the blood against any unit area of the vessel wall

36
Q

What can pressure be measured with?

A

mercury manometer

electronic transducers

37
Q

What is resistance?

A

impediment to blood flow in a vessel

38
Q

What variable determine resistance?

A

vessel radius
blood viscosity
vessel length

39
Q

What is cardiac output?

A

rate of blood flow through entire circulatory system, 100 ml/sec

40
Q

What is the pressure difference from systemic arteries to systemic veins?

A

100 mm Hg

41
Q

In conditions when vessels are strongly constricted, total peripheral resistance may rise to _____

A

4 PRU

42
Q

When vessels are greatly dilated, the resistance can fall to as little as _____

A

0.2 PRU

43
Q

What is the mean pulmonary arterial pressure?

A

16 mm Hg

44
Q

What is the mean left atrial pressure?

A

2 mm Hg

45
Q

What is conductance?

A

measure of blood flow through a vessel for a give pressure difference

46
Q

conductance is ______ proportional to diameter

A

directly

47
Q

What is Poiseuille’s Law?

A

V = π p r4 / 8 η l

48
Q

What is the equation for resistance for blood vessels arrange in parallel

A

1/Rtotal= 1/R1 + 1/R2 +1/R3…..

49
Q

What does amputation of a limb or removal of a kidney do?

A

removes a parallel circuit:
reduces total vascular conductance
reduces total blood flow
increases total peripheral vascular resistance

50
Q

What circulations are arranged in parallel?

A
brain
kidney
muscle
gastrointestinal
skin
coronary circulation
51
Q

What is viscosity?

A

measure of the fluid’s internal resistance

52
Q

Greater the viscosity, ______ the resistance

A

greater

53
Q

What is the prime determinant of blood viscosity?

A

hematocrit

54
Q

Anemia _____ viscosity

A

decreases

55
Q

Polycythemia _____ viscosity

A

increases