Lecture 10: Peripheral Blood

Question 1

Three layerts of blood draw

Answer 1

55% Plasma
1% Buffy(WBC)
45: hemo(Packed RBCS)

Question 2

Answer 2

Erythrocytes (RBCs)
Leukocytes (WBCs)
Blue Arrow: Platelets (thrombocytes)

Question 3

Answer 3

Erythrocytosis – ↑ % RBCs

Question 4

Answer 4

Anemia – ↓ % RBCs

Question 5

Answer 5

Leukocytosis – ↑ % WBCs

Question 6

Answer 6

Spherocytosis

Question 7

Answer 7

Lacks nucleus & most organelles (therefore not a cell, so an erythrocyte is called a formed element)

Question 8

Answer 8

Platelet: 2nd most abundant ~2um
Blood clotting(hemostatis)

Question 9

Thrombocytopenia

Answer 9

is characterized by low levels of platelets. Symptoms may include easy bleeding or bruising.

Question 10

Granules are secreted for:

Answer 10

Coagulation
▪ Platelet adhesion
▪ Vasoconstriction
▪ Blood vessel repair

E- even dense

Question 11

Answer 11

Neurtophill

Question 12

Answer 12

Eosinophil

Question 13

Answer 13

Basophils

Question 14

Answer 14

Lympocytes

Question 15

Answer 15

Monocyte

Question 16

Answer 16

Granulocyte: neutrophil
BILOBED NUCULES

Question 17

Neutrophils FXN

Answer 17

Most Abundant. Phagocytoses bacteria and O2 depending.

two types of granules: Azurophillic(lysosomes) and Specific e-dense

Question 18

Granulocyte: eosinophil

Answer 18

Bi- (or tri-) lobed nucleus
Specific granules –
Electron-dense crystalloid body
**Major basic protein **released by exocytosis –
has toxic effect on parasites

Question 19

Answer 19

eosinophil

Question 20

Answer 20

eosinophil

Question 21

elevated eosinophil counts in a blood panel may indicate of

Answer 21

parasitic infection

Question 22

Granulocyte :basophil

Answer 22

Least numerous leukocyte or blood cell
hypersensitivity (allergic) reaction…Similar to MAST
Bi- (or tri-) lobed nucleus
Heparin (anticoagulant [GAG]) Histamine (↑ blood flow)

Question 23

Answer 23

Basophil

Question 24

Answer 24

Basophil

Question 25

Agranulocyte: lymphocyte

Answer 25

B lymphocyte – secrete antibodies as plasma cells T lymphocyte – recruit & activate phagocytic cells Natural killer cell – kill virally-infected or some cancer cells

Question 26

Answer 26

Lymphocyte: Basic cytoplasm small amount of cyto compared to nucules

Question 27

Answer 27

Lymphocyte

Question 28

Precursor to macrophages

Answer 28

monocytes “Fat” C-shaped nucleus

Question 29

Answer 29

Macrophage to monocyte

Question 30

Answer 30

A B. RBC C. Basophil D. Eosniophil E. Neutrohpil F. Lympohocyte G. Macrophage