Lecture 13 Cartilage and bone

Question 1

Cartilage Cell Type

and Types

Answer 1

Chondrocytes
Hyaline, Elastic and Fibrocartilage

Question 2

Bone Cell Type(s) and Types

Answer 2

Osteoclast, Osteocytes and Osteoblast
Woven/lamellar

Question 3

What type of cells are spaces are chondrocytes found in

Answer 3

Lacunae

Question 4

What is the white

Answer 4

Lacunae

Question 5

What are these “clusters called” and where are they found?

Answer 5

Isogenous groups and grow in intersital growth… Chondrocytes..Mitotic growth

Question 6

What is the ECM of Cartilage composed of?

Answer 6

GAGS, Proteoglycans, TYPE 2 Cartilage
AVASCULAR relys on diffusion

Question 7

What is the black arrow and what type of growth?

Answer 7

Perichondrium allows for appositional growth,

DENSE IRREGULAR.

Not found in Fibrocartilage or Articular cartilage

Question 8

What is this and where is it found

Answer 8

Hyaline Cartilage and found in most areas like joints and trachea

Question 9

What is this?

Answer 9

Fibrocartilage found in the vertebral spine

Question 10

What type of cartilage is this and where is it found

Answer 10

Elastic Cartilage and found in the ears

Question 11

What is the purpose of Hyaline Cartilage

Answer 11

FXN: resist compression, EXM attracts water, Articular Cartilage is hyaline cartilage of joints.

Question 12

What is this

Answer 12

Articular Cartilage(Hyaline)
Glassy Apperance, pink to nlue stain.
**NO PERICHONDRIUM **

Question 13

What is this

Answer 13

Articular Cartilage(Hyaline)
Glassy Apperance, pink to nlue stain.
**NO PERICHONDRIUM **

Question 14

What is this.
Hint notice the top

Answer 14

Hyaline Cartilage
HAS PERICHONDRIUM

Question 15

What is this? and FXN

Answer 15

elastic cartilage uses Orcein and Hematoylin/Orcein to stain

FXN+ Elastic support

Question 15

What is this? and FXN

Answer 15

elastic cartilage uses Orcein and Hematoylin/Orcein to stain

FXN+ Elastic support

Question 16

What is this? and its FXN

Answer 16

Fibrocartilage and used for Tension and Compression

NO PERICHONDRIUM
Chonrdocytes line up in a row

Question 17

Cartilage can resist tremendous compressive force, but once injured, has limited ability to repair due to _______

____ will result in _____(Scar tissue)

Answer 17

Avascular
Perichondrium will result in scar tissue.

Question 18

Woven (Immature) Bone

Answer 18

Initial bone formed; fracture repair
* Poorly organized type I collagen
* Grows rapidly

Question 19

Lamellar (Mature) Bone

Answer 19

Distinct layers (lamellae) present
* Well-organized type I collagen
* Grows slowly

Question 20

1 and 2

Answer 20

Lamellar and Woven

Question 21

What is this

Answer 21

Haverisan Canal and Osteon

Question 22

Basic unit of Bones

Answer 22

Osteons (Secondary osteons, Haversian System)
* basic unit of bone
* rings of lamellar bone around a central canal

Question 23

What is the purpose od teh central Canal

Answer 23

contains blood vessel & nerves
* diffusion through canaliculi

Question 24

Which is the perforating Canal and what is its purpose

Answer 24

connect central canals with each other & vessels in the periosteum and marrow cavity * perpendicular to central canals

Question 25

What are the Black Dots.

Answer 25

Lacunae for bones

Question 26

What is the overall and its two layers

Answer 26

Periosteum Outer fibrous(dense CT) and Inner cellular(Stem cells)

Question 27

What type of fibers attach muscle to bone?

Answer 27

Sharpey

Question 28

What are the yellow lines?

Answer 28

Endosteum a monolayers of cells, STEM CELLS

Question 29

MSC lineage.

Answer 29

Osteoprogenitor cell --> Osteoblast --> Osteocyte(In matrix)

Question 30

HPS Lineage

Answer 30

HPSC to OsteoClast

Question 31

What is this

Answer 31

Osteoblast

Question 32

What are these

Answer 32

Question 33

What do osteoblast secete

Answer 33

Osteoid

Question 34

Answer 34

Osteoblast Osteoid Mineralizing bone Ostocyte

Question 35

Where do osteoclast lay at?

Answer 35

Reside in resorption cavities (Howship’s lacunae)

Question 36

Osteoclast Zones Which is the clear Zone(site of Adhesion) Ruffled zone((Folded Plasma)

Answer 36

Black is ruffled and Green is clear zone . Lysosomal enzymes help break down

Question 37

PTH vs Calcitonin

Answer 37

PTH helps increas CA2 levels binds to osteoblast. Calictonin Helps to decrease calciulm levels inhibts by binding to osteoclast