Lecture 12: Induction Agents Flashcards
What monitoring should you have on patient before inducing
ECG, pulse ox, BP
Why pre-oxygenate
Saturate blood with O2 so when you induce you have time to intubate because they come apneic fast
Why do we intubate
- Airway protection
- Ventilation
- Maintenance under GA
How do we assess anesthesia depth
- Jaw tone
- Palpebral reflex
- Eye position
At what depths do we prefer our sx anesthesia patients
1-light or 2-medium
Don’t want too deep
After induction what do you do
- Hook up to anesthesia machine
- Turn on O2
- Leak check
- Turn on inhalant
What is the mechanism of action of propofol
GABA agonist
What are the affects of propofol on CNS
Depression, decrease ICP, anticonvulsant
What are the cardiovascular effects of propofol
Decrease BP d/t vasodilation
What are the respiratory effects of propofol
Depression, apnea
T or F: propofol relaxes muscle
True but can see myoclonic movements
T or F: propofol provides analgesia
False
What is the route of administration for propofol
IV or else ouchie
What is the onset of effect and duration of action for propofol
Onset: 20-30 seconds
Duration: 5-10 minutes
What is mg/kg for propofol alone and then with other induction agents
1-6mg/kg alone
1-4mg/kg with co-inductions
What is the mechanism of action of alfaxalone
GABA agonist
What are the CNS effects of alfaxalone
Depression, decrease ICP
What are the cardiovascular effects of alfaxalone
HR maintained or increased
Hypotension d/t vasodilation
What are the respiratory effects of alfaxalone
Depression, apnea
T or F: alfaxalone relaxes muscles
True, myoclonic activity c an be seen though
T or F: alfaxalone provides analgesia
False
What are the routes of administration for alfaxalone
IV, IM
What is the onset of effect and duration of effect for alfaxalone
Onset: 30-45 seconds
Duration: 5-10 mins
What is the mg/kg dose for alfaxalone alone and then with other co-inductions
Alone: 0.5-4mg/kg
Combined: 0.5-2mg/kg
