Lecture 2 Anatomy (CNS Overview) Flashcards
(104 cards)
What is the brain made up of?
100 billion neurons
1 trillion neuroglia
-Neurons are primarily interneurons (associative) involved in associative function (intellect, emotions, behavior, and memory)
Brain development:
Describe the stages -
Ectoderm -> neural fold -> neural tube -> 3 primary vesicles -> 5 secondary vesicles
5 Principle parts of the brain (derived from secondary vesicles):
- Telencephalon - cerebral hemispheres, basal ganglie, limbic system
- Diencephalon - thalamus, hypothalamus, epithalamus
- Mesencephalon (midbrain) - cerebral peduncles, corpus quadrigemina
- Metencephalon - cerebellum, pons
- Myelencephalon - medulla oblongata
Brain stem (parts):
- Medulla oblongata (myelencephalon)
- Pons
- Midbrain (mesencephalon)
Protective covering of brain:
Start with scalp -
1. Scalp - skin, CT, aponeurosis, lipid, and periosteum 2 Cranial bones (skull) 3. Epidural space with far 4. Dura matter 5. Subdural space - with interstitial fluid 6. Arachnoid mater 7. Subarachnoid space - with CSF 8. Pia matter
Folds of the dura matter (hold brain in place)
Falx cerebri -
Falx cerebelli -
Tentorium cerebelli -
Falx cerebri - sagittal between cerebral hemispheres
Falx cerebelli - sagittal between cerebellar hemispheres
Tentorium cerebelli - transverse between cerebrum and cerebellum
What is brain’s normal fuel source and how much does it use during rest?
Glucose (unable to store)
Uses 20% of bodies oxygen and glucose
Blood brain barrier composed of 3 parts:
- Tight junctions between blood vessel endothelial cells
- Continuous endothelial cell basement membrane
- Astrocytes (neuroglia) wrapped around endothelial cell basement membrane
What can/can’t cross BBB?
Not found in which organs (give general name and name 3 organs)?
Can - lipid soluble, hydrophobic substances Can't - Water, hydrophilic substances Circumventricular organs: 1. Hypothalamus 2. Pituitary 3. Pineal Gland
Medulla Oblongata (Myelencephalon): Overall Functions -
- Contains nuclei for vital centers and cranial nerves
2. Signal Propagation via ascending (sensory signals) and descending (motor signals) tracts
Medulla Oblongata (Myelencephalon): Nerve tracts -
Nerve tracts - (bundles of axons) both sensory (ascending) and motor (descending)
Medulla Oblongata (Myelencephalon): Pyramids -
Pyramids - paired ventral surface ridges that contain motor descending tracts
Medulla Oblongata (Myelencephalon): Decussation of pyramids -
Decussation of pyramids - motor tracts from the right brain cross to control muscles on the left side and motor tracts from left brain cross to control muscles on the right side
*motor
Medulla Oblongata (Myelencephalon): Olives -
Olives - paired bulges lateral to pyramids which contain the inferior olivary nuclei which links brain and spinal cord motor signals to the cerebellum for perception of time
Medulla Oblongata (Myelencephalon): Fasciculus gracilis and fasciculus cutaneous -
Fasciculus gracilis and fasciculus cutaneous - ridges found on dorsal medulla which relay sensory ascending input to opposite side of the brain
Medulla Oblongata (Myelencephalon): Decussation of the medial lemniscus -
Decussation of the medial lemniscus - crossover of ascending sensory input to the contralateral brain hemisphere
*sensory
Medulla Oblongata (Myelencephalon): Nuclei
Nuclei - masses of neuronal cell bodies
- Vital body functions: cardiovascular, respiratory
- CN nuclei for CN 8, 9, 10, 11, & 12
Pons: Where is it found? What part of brain is it? Contains - Functions -
- Found on ventral surface of brain stem
- Apart of metencephalon with cerebellum (which is not apart of the brain stem)
Contains - CN nuclei 5, 6, 7 and ascending and descending tracts
Functions - information relay for cerebellar hemispheres
Midbrain:
Where is it found?
What CN?
- Mesencephalon
- CN 3, 4
Midbrain:
Superior colliculi -
Superior colliculi - reflex movement of eye, head, and neck to visual and other stimuli
Midbrain:
Inferior colliculi -
Inferior colliculi - reflex movement of head and neck to auditory stimuli
Midbrain:
Cerebral peduncles -
Cerebral peduncles - contain descending motor axon tracts from cerebral hemispheres to spinal cord, medulla and pons
-Ascending sensory axons going to cerebrum
Midbrain:
Cerebral peduncles -
Cerebral peduncles - contain descending motor axon tracts from cerebral hemispheres to spinal cord, medulla and pons
-Ascending sensory axons going to cerebrum
Midbrain:
Red nucleus and substantia nigra -
Red nucleus and substantia nigra - function to modify motor signals