Lecture 21

Question 1

Why might we need to estimate frequencies of genotypes in a population?

Answer 1

• predict inheritance/how many people get the disease
• predict proportion of carriers

Question 2

What is the Hardy Weinberg equation? What is it used for?

Answer 2

p^2 + 2pq + q^2 = 1
Used to predict genotypes in a population

Question 3

1 in 2500 children are born with cystic fibrosis.
What proportion of the population are carriers for the disease?

Answer 3

4%

Question 4

If 1 in 10,000 children is born with Tay-Sachs disease, what
percentage of the population are expected to be carriers for this
autosomal recessive disease?

Answer 4

2%