Lecture 23: Lactation Flashcards Preview

PSIO 469 Exam 04 > Lecture 23: Lactation > Flashcards

Flashcards in Lecture 23: Lactation Deck (47):
1

Which part of the mammary gland consist of the "cluster of milk containing the alveoli?"

Secretory Lobule

2

Which synthesize and secrete milk

Alveolar Cell

3

Which contract to decrease the volume of alveoli

Myoepithelial cell

4

What are the 5 steps of milk synthesis and secretion

1. Secretory Pathway
2. Transcellular endocytosis/exocytosis
3. Lipid Pathway
4. Transcellular salt and water transport through channels and transport
5. Paracellluar pathway for ions and water

5

What 3 substances are in the secretory pathway?

1. Casein
2. Salts
3. Sugar

6

What 3 substances are in the Transcellular Endocytosis/Exocytosis?

1. Immunoglobulins
2. Hormones
3. Growth Factors

7

What does Mammogenic Hormones do?

Promote Cell Proliferation

8

What 4 substances are affected by Lobulo-Alveolar Growth?

- Estorgen
- Growth Hormones
- Cortisol
- Prolactin

9

What 3 substances are affected by Ductal Growth?

- Estrogen
- Growth Hormone
- Cortisol

10

What do Lactogenic Hormones do?

Promote initiation of milk production by alveolar cells

11

What 5 hormones affected by Lactogenic?

- Prolactin
- Human Chorionic Somatomammotropin
- Cortisol
- Insulin (affect premies)
- Thyroid Hormones

12

What other hormones are in the same family of Somatomammotropin

GH and Prolactin

13

What two hormones inhibit milk production?
What do they do?

Estrogen: Removal of inhibition with parturition permits lactation
Progesterone: Combination OCPs may interfere with lactation

14

What does Galactokinetic Hormones do? name a hormone affected by it?

Promote contraction of myoepithelial cells and milk ejection
- Oxytocin

15

What does Galactopoietic Hormones do? what 2 hormones affected by it

Maintain milk production after it has been established
- Prolactin and GH

16

What is rBST and rBGH?
what do they do?

- recombinant Bovine Somatotropin
- recombinant Bovine Growth Hormones
- increases milk yield in lactating cows

17

Which hormone removes inhibition?

Dopamine

18

Which hormone affects the Epithelial Cells?

Prolactin

19

Which hormone affects the Myoepithelial cells?

Oxytocin

20

Lactation Stimuli and Hormone Release
____ can become conditioned to stimuli other than suckling.

Lactation

21

Lactation Stimuli and Hormone Release
_____ is not secreted in response to anticipatory stimuli?

PRL

22

Milk Consumption
Human Colostrum's nutrients consist of?
When is this made?

Low Fat and Carbs, High proteins and lost of antibodies
- Made the first 5 days post-partum

23

Milk Consumption
Human milk's nutrients consist of?

High Fat and Carbs, low protein, fat soluble vitamins, antibodies

24

Milk Consumption
Cow's milk's nutrients consist of?

3x more proteins ( due to casein), high electrolyte content

25

Milk Consumption
Infant Formula's nutrients consist of?

More protein, less fat, more electrolytes and no cells

26

AAP recommends that babies be breastfed?

~ first 6 months of life

27

Baby needs no additional foods, (except _____) or _____ unless medically indicted

Vitamin D
Fluids

28

Babies should continue to breastfeed:

for a year and for as long as it is mutually desired by mother and baby

29

What is Lactational Amenorrhea?
What is Anovulation?

Lack of menstrual cycle
Lack of ovulatory cycles

30

Durational of lactational amenorrhea is affected by:

high variability, due to frequency and duration of lactation

31

Plasma LH is undetectable on day__ post partum

7

32

After 4 weeks postpartum:

No LH pulses in 6 out of 9 fully breastfeeding women

33

After 8 weeks postpartum:

LH pulses in 9 out of 11 fully breastfeeding women

34

Limited estradiol at 16 weeks indicates:

presence of a follicle

35

Follicle growth noted after ______ but associated with inadequate _____ _____

menses
corpus luteum

36

This resumes after complete weaning?

Normal menstrual cycle

37

This gene codes for Kisspeptin:

KiSS-1

38

Lactation suppresses _____ ____ expression in ARC

KiSS-1 mRNA

39

An injection of this stimulates pulsatile LH secretion in lactating rats:

Kisspeptin-54

40

____ neurons are capable of responding of _______, suggesting lactation inhibits_____ expression to _____ of __ secretion

GnRH; Kisspeptin
Kisspeptin; inhibits
LH

41

What 6 reasons to use a breast pump?

1. Return to work
2. Travel or any other separation from baby
3. allow father or others to bottle feed baby
4. Collect milk to feed to premature baby
5. Boost milk supply
6. Poor suckling behavior by baby

42

What does Donor Milk banking do?

collection, screening, processing and distribution of human milk from volunteer breastfeeding mothers

43

What does Informal Milk Sharing do?

Sharing expressed milk with friends, neighbors or acquaintances but can spread potential diseases and bacteria due to inadequate screening

44

Name the 4 types of breast implant surgery?

1) Periareolar ("smile' incision around areola)
2) Transaxillary (armpit)
3) Transumbilical (though bellybutton)
4) Inframammary Fold (underneath breast)

45

Which of the 4 incisions is bad and why?

Periareolar, because it can cut or damage nerves in the duct system

46

______ placement is above the chest wall muscle.
______ placement is below the chest wall muscle.

Subglandular
Submuscular

47

Implant may exert ______ on _____ tissue cause pain, _____ and/or _____ and physically blocking ____ thus reducing _____ ______

pressure; glandular
atrophy; necrosis; ducts
milk production