Lecture 25 Flashcards

The mechanics of breathing

1
Q

what does surfactant do and when is is produced?

A

it decreases the tension so the alveoli don’t collapse and it made close to birth of the baby

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2
Q

Law of Laplace

A

P=2T/r

if the tension of 2 bubble are the same, the pressure of the smaller will be greater due to its smaller radius

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3
Q

Why do smaller alveoli have more surfactant?

A

so its easier for them to inflate

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4
Q

What happens to alveoli pressure when inhaling and exhaling?

A

it decreases as you inhale and increases as you exhale

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5
Q

What is the pressure of interpleural tissues

A

Negative and increases negativity as breathing occurs

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6
Q

Why is the pressure of the intrapleural membrane negative?

A

the visceral membrane is following the lung and the partial tissue is on the chest wall. the lungs always want to be recoiled so when you breathe, the chest pulls the partial away from the lung and the lung pulls in towards itself increasing the negativity (more negative). At rest, the interpleural pressure is -4mmHg

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7
Q

Pneumothorax

A

A collapsed lung, when air enters the pleural sac, atmospheric pressure is now the same as in interpleural pressure. the chest well expand and the wall inflates.

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8
Q

What happens to volume and pressure during inhalation

A

the volume increases, decreasing the pressure

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9
Q

What happens to volume and pressure during exhalation?

A

the volume decreases increasing the pressure

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10
Q

Lung Compliance

A

the ability for the lung to stretch

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11
Q

What diseases affect lung compliance

A

fibrotic diseases like making extra collagen because it stiffens the lung

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12
Q

Lung Elastance

A

ability of the lung to spring back after being stretched?

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13
Q

what disease affect lung elastance

A

emphysema a loss of elastin tissue

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14
Q

How does muscles move in inspirations

A

The diaphragm moves down and the eternal intercostal muscle move out increasing the volume of the lung which decree the pressure allowing air to move inside

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15
Q

How does muscles move in expirations

A

The abdominal muscles and the internal intercostal muscles pulls in by ribs and the diaphragm moves up decreasing the volume and increasing the pressure

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16
Q

Spirometry

A

device to measure pulmonary function

17
Q

Tidal Volume (Vt)

A

500ml how much air breathe in and out during a normal inhalation

18
Q

Residual Volume (RV)

A

1200ml - air in lungs we can’t breathe out

19
Q

Expiratory Reserve Volume (ERV)

A

1100ml - extra air we can force to expire

20
Q

Inspiratory Reserve Volume (IRV)

A

3000ml- extra air we can breathe in

21
Q

Total Lung Capacity

A

VT+RV+IRV+ERV

22
Q

Inspiratory Capacity

A

VT + IRV

23
Q

Vital Capacity

A

VT+IRV+ERV

24
Q

Functional capacity

A

ERV + RV

25
Q

Ventilation Volume

A

Ventilation rate * (Tidal Volume- dead space)

26
Q

What is dead space and how much?

A

The air breathed in the tidal volume that does not reach the alveoli (trapped in the trachea and bronchi)and 150mL