Lecture 26 and 27 Flashcards
(29 cards)
describe main glucose transporters
name an active glucose transporter
how is insulin release mediated by glucose
what are the drug targets on insulin release
Pro - insulin?
insulin and glucagon?
describe the incretin effect and vs in T2DM
describe the mechanism of action of DPP4 inhibitor and GLP-1 receptor agonists on insulin release
describe the actions of insulin on carbs, fat and protein
energy storage?
desribe krebs cycle for beginners
what hapens in ketogenesis, what does this lead to?
describe hypoglycimia adn its two stages
what are the causes of hypoglycamia?
what is insulin resistance and what is it associated with?
what is metabolic syndrome and its risk factors
what has contributed to obesogenic environment?
how to recosgnise a patient with insulin resistance?
what causes insulin resistance
are adiponectin and/ore resistin implicated in insulin resistance?
explain this
pathogenesis of insulin resistance
what are the consequences of insulin resistance
whats going on?