Lecture 26: Invasive Fungal Infection Flashcards
(29 cards)
Nephropathy consider what fungal organism
Systemic Aspergillosis
hepatopathy consider what fungal organism
histoplasmosis
ctyopenias consider what fungal organism
histoplasmosis
what fungal organism likes to cause discospondylitis
aspergillosis
what’s this
blastomyces
what this
histoplasmosis
what this
Cryptococcus
what this
aspergillosis
what is the primary biomarker for blastomyces and best sample type
antigen EIA- Galactomannan
Sample type: urine
what is the secondary biomarker for blastomyces
antibody IgG EIA
what is the primary biomarker and best sample type for histoplasmosis
antigen EIA- galactomannan
Urine best sample type
what is secondary biomarker for histoplasmosis
antibody IgG EIA
what is the primary biomarker for cryptococcus and what is test of choice
antigen- glucoronoxylomannan
Test: latex agglutination
what is primary biomarker for systemic aspergillosis and best sample type
antigen- galactomannan
Best sample: serum
what commonly used in vet med can cause false + to aspergillosis biomarker test
Vetivex pHLyte (fluids)
what is primary biomarker for sinonasal aspergillosis
antibody AGID
t or f: a negative biomarker test for sinonasal aspergillosis does not rule out SNA
true
what is tx for mild-moderate out patient histo
itraconazole > fluconazole
what is tx for severe life threatening histo, blasts, cryptococcus and aspergillosis
amphotericin B
what is salvage/rescue tx for histo
posaconazole >voriconazole
Or
Terbinafine +azole
what is mild-moderate outpatient tx for blasto
itraconazole > fluconazole
what is salvage/rescue tx for blasto
posaconazole > voriconazole
Or
Terbinafine and azole
what is tx for mild-moderate outpatient cryptococcus
fluconazole > itraconazole
what is salvage/rescue tx for cryptococcus
posaconazole > voriconazole
