Lecture 3 Flashcards
(21 cards)
How do go get a genetic disorder
Inherited
What does the NH test for (6)
- Recessive mutation
- Still-born calves
- Large cranium
- Little or no brain
- Foetal deaths
- Noted in US Angus
How are recessive genetic disorders caused
By recessive alleles when a person is homozygous recessive for that trait
What is a carrier
A person who is heterozygous for a trait does not express the trait but can pass the trait to their offspring
What is albinism
No colour in the skin, eyes and hair
What is cystic fibrosis
Causes a thick, sticky mucus to build up in the lungs and digestive tract
What is galactosemia
Inability of the body to break down the simple sugar galactose
What is Tay-Sachs disease
Deadly disease of the nervous system that primarily affects people of mostly Eastern European and Jewish Decent
What is the cause for CF
Deletion of 3 bases on chromosome 7
What is the problem with sickle cell anaemia
Cannot carry enough oxygen
What is Autosomal Dominant Disorder
All affected individuals have an affected parent. Normal siblings of affected individuals do not transmit disease
What is Huntington’s disease
Causes nerve cells in the brain to degenerate, causing gradual loss of function of the brain
What is Achondroplasia
A disorder that affects growth of bones and causes dwarfism
What is Polydactyly
A condition resulting in an extra number of fingers and toes
Explain the X-linked recessive
Passed from affected males through their daughters. No transmission directly from father to son
Explain the X-liked dominant
Affected males with normal spouses have normal sons and all affected daughters
Define Euploidy
Addition or loss of complete chromosome sets. Fatal to embryo
What does MOET stand for
Multiple ovulation and embryo transfer
What does ONBS stand for
Open nucleus breeding system
Where is Neuropathic Hydrocephalus seen (what animal)
Angus cattle
Define inbreeding
Increasing the % of homozygosity
