lecture 30 Flashcards

(31 cards)

1
Q

What is the primary role of the pre-frontal cortex?

A
  • provides executive control for working memory and cognitive control
  • it tells other brain regions what to do
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2
Q

what are the PFC subregions

A
  • dorsolateral PFC
  • ventrolateral PFC
  • medial PFC
  • rostral PFC
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3
Q

Anatomically, where is the PFC located and what proportion of the cerebral cortex does it make up?

A
  • it is located in the anterior region of cortex
  • it constitutes approximately 1/3 of the cerebral cortex
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4
Q

What are some consequences of damage to the PFC

A
  • damage results in impaired higher intellectual activity and loss of ability to plan and organize
  • behavioural issues
  • problems with goal-directed behaviour and inhibition
  • dysfunction correlated with schizophrenia, ADHDm and possibly depressive disorder, and substance abuse
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5
Q

What functions are associated to a well functioning PFC

A
  • feeling of guilt/ remorse and interpreting reality
  • concentration, organization, judgement, reasoning, decision-making, creativity, regulating behaviour, abstract thinking
  • planning, judgement, insight, working, memory, cognitive control and behavioural inhibition
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6
Q

what kind of therapies is the PFC important in

A
  • cognitive behavioural therapy
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7
Q

What is working memory?

A
  • type of short-term memory
  • a ‘holding station’ to remember something long enough for it to be used to affect behaviour
  • temporary retention of information just experienced or retrieved from long-term memory
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8
Q

What is cognitive control?

A
  • manipulation and application of working memory for planning, task switching, attention, inhibition of inappropriate behaviour
  • ex. studying 306 notes
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9
Q

what is transient memories?

A
  • short lasting mental representation
  • it is the first stage where information from the world enters your consciousness and potentially becomes part of long-term memory
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10
Q

What are the two types of transient memories

A

sensory: brief, transient sensation you just experienced (e.g. visual sensory memory), not dependent on PFC

short-term memory: memory that holds small amount of information for a brief amount of time (e.g. remembering a phone number just long enough to dial it), critical on PFC, affected by rehearsal, encoding and distractions

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11
Q

what is the capacity of our short-term memory

A
  • “magic number 7”: on average 7 +/- 2 can be held
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12
Q

what is working memory used for?

A
  • used for goal-directed behaviours or retrieving other information from LTM
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13
Q

What are the two types of information stored separately in working memory?

A
  • visuo-spatial (images and space) and verbal-phonological information (sounds and words)
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14
Q

how is working memory controlled?

A
  • by the central executive which functions to monitor and manipulate cognitive control
  • it adds, deletes, selects, manages traffic between STM and LTM; reasoning, problem solving and planning
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15
Q

what is the DLPFC main function?

A
  • provides executive function such as problem-solving, inhibiting automatic responses that adjust your behaviour when you notice a conflict
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16
Q

What is the Stroop Effect?

A
  • the stroop effect is a psychological phenomenon when naming a color is easier and faster the word and the color are congruent or when the word is a random word rather than the name of a color, but more slower if the word and the color are not congruent
17
Q

How does the DLPFC help during the stroop task

A
  • It detects conflict between reading and color-naming, inhibits the automatic reading response, and helps adjust behavior.
18
Q

what is cool executive function?

A
  • it is associated with relatively non-affective abstract situations such as logic and critical analysis or inhibitory control
  • not using emotional or motivational components
  • DLPFC
19
Q

What is the hot executive function?

A
  • it is associated with affective, motivationally significant conditions, like a process driven by emotion
  • VMPFC
20
Q

Who was Penfield’s sister and what happened to her? And what did she develop

A
  • she was an accomplished chef who lost her ability to plan and organize tasks after having a tumor removed from her prefrontal cortex.
  • she developed dysexecutive syndrome
21
Q

what is dysexecutive syndrome?

A
  • a condition where the ability to think and plan are disrupted
  • deficits in the executive functions and working memory
22
Q

Which cognitive abilities often remain intact in people with dysexecutive syndrome?

A
  • long-term memory and skill learning ability
23
Q

What kind of memory is typically impaired in dysexecutive syndrome?

A
  • Working memory and short-term memory (STM), such as digit span tasks.
24
Q

What is the Tower of Hanoi task, and why is it relevant?

A
  • it is a problem solving task that requires planning and inhibition
  • people with PFC damage can’t complete it due to impaired executive function
25
The VMPFC/orbitofrontal cortex are involved in...
- emotional control, personality, social and affective executive functions
26
What outcome would result from a dominant vs. non dominant lesion
- dominant (often, left) = negative affect (e.g. sadness) - non-dominant = euphoria (e.g. impulsivity)
27
Damage to the VMPFC results in
- excessive emotion, poor impulse control, poor social interactions - innapropriate crying, anger, laughing, sexual behaviour - dishinbition
28
What happened to Phineas Gage? And what did it reveal
- a young railroad construction foreman sustained an injuring where a tamping rod was driven through his left pre-frontal cortex - he sustained a left ventromedial dominant lesion - prior to the accident, he known to be hard working and efficient - following the accident he was frequently angry, stubborn, displayed impulsivity, lacked planning and had socially inappropriate behaviour - this illustrated that the PFC is involved in emotional control, personality, social and affective executive functions
29
What is the visual oddball task?
- in a visual oddball task, participant respond to a rare target among frequent non-targets
30
Describe the oddball effect on the waves of an EEG? And what this means
- P2 wave remains the same for frequent and infrequent stimulus - P3 wave is larger for the rare target This is though to reflect that cognitive control functions such as attention and response monitoring are mediated by the pre-frontal cortex
31
What the EEG in a criminal psychopath look due to the oddball effect?
- psychopaths showed reduced P3 amplitude to rare target - this reflects reduced cognitive control and inhibition, increased impulsivity and atypical prefrontal function