Lecture 4 Flashcards

(7 cards)

1
Q

What are the main types of infectious agents?

A
  • viruses
  • bacteria
  • fungi
  • protozoa
  • helminth parasites
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2
Q

Eukaryotes vs prokaryotes

A

eukaryotes:

  • well defined cytoskeleton
  • membrane bound organelles
  • well organised
  • larger
  • diploid/haploid

prokaryotes:

  • cell wall of peptidoglycan
  • no membrane bound organelles
  • circular chromosome
  • haploid
  • less well defined cytoskeleton
  • smaller
  • simpler
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3
Q

Viruses - features and examples

A
  • infectious obligate intracellular parasites
  • have RNA/DNA
  • divide by budding out of host cells
  • various routes of infection
    E.G. HIV, SARS, Influenza, Polio
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4
Q

Bacteria

A
  • Replicate by binary fission
  • Prokaryotes
  • Have chromosomes - nuclear area where DNA is contained is the nucleoid
  • Various routes of infection
  • E.G. shigella causes shigellosis (faecal oral route and enters cell via vacuole and replicate intracellular)
    Neisseria Meningitidis can cause septicaemia
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5
Q

Fungi

A
  • eukaryotes
  • occur as yeasts (single cell), filaments of both
  • yeast bud to divide
  • have filaments called hyphae which have cross walls/septa (between cells in hyphae)
  • E.G. Candida albicans causes Candida
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6
Q

Protozoa

A
  • These are unicellular eukaryotic organisms
  • They are parasites that can infect the intestines, the blood and other tissues
  • They replicate in the host via binary fission or by formation of trophozoites inside a cell
  • They have a complicated life cycle involving two hosts
  • Infection is acquired by ingestion or through a vector, such as an insect
  • Two examples are malaria (Plasmodium) and leishmaniasis (Leishmania)
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7
Q

Helminth parasites

A
  • These include roundworms, tapeworms and flatworms
  • They are multicellular eukaryotic organisms
  • They are visible to the naked eye and can exist outside the host
  • Can have simple or complex life cycles involving different hosts
  • Examples include Ascaris (round worm called Ascaris lumbricoides) and schistosomiasis (flatworm called schistosome)
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