Lecture 4 - Mydriatics Cycloplegics Flashcards Preview

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Flashcards in Lecture 4 - Mydriatics Cycloplegics Deck (31)
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1

Hormones including dopamine, epinephrine and norepinephrine; produced from tyrosine in postganglionic fibers of the autonomic nervous system and the adrenal medulla

Catecholamines

2

Catechol-O-methy transferase; an enzyme of catecholamine metabolism

COMT

3

Monoamine oxidase; an enzyme of catecholamine metabolism

MAO

4

Pupillary contraction

miosis

5

Pupillary dilation

mydriasis

6

Paralysis of the ciliary body musculature responsible for accommodation.

cycloplegia

7

Which Ig in the bloodstream reacts with the antigen leading to histamine release, bronchoconstriction, vasodilation and swelling?

IgE

8

Fight and Flight is regulated by the __________ or ____________ branch of the ANS.

Sympathetic/adrenergic; autonomic nervous system

9

Rest and Digest is regulated by the ___________ or ____________ branch of the autonomic nervous system.

Parasympathetic / cholinergic

10

Epinephrine and Norepinephrine are part of the ________ ANS NTs.

sympathetic

11

Presynaptic +a2 receptor stimulates/inhibits signal propagation

inhibits

12

Stimulation of a1: vasoconstriction/vasodilation

vasoconstriction

13

Stimulation of b2: vasoconstriction/vasodilation

vasodilation

14

Stimulation of b2 in lungs? dilation or constriction?

bronchodilation

15

Stimulation of b1 in heart: increase/decrease contractility and conduction.

increase contractility and conduction

16

In the liver stimulation of b2 causes?

glucogenolysis; break down of glycogen and dumping into the bloodstream

think of it facilitating fight/flight.

17

In the pancreas stimulation of b2 causes increase/decrease in insulin release.

increase in insulin release

18

In the pancreas stimulation of a2 causes increase/decrease in insulin release.

decrease in insulin release

19

In the iris, stimulation of a1 causes _______.

mydriasis

20

In the ciliary body stimulation of b2 causes constriction/relaxation and increase/decrease in aqueous production.

Relaxation and increase in aqueous production

21

In the ciliary body stimulation of b2 or a2 causes increase/decrease in aqueous production.

decrease aqueous production

22

What does a1 receptor respond to?

NE > E

23

What does a2 receptor respond to?

E >/equal NE

24

What does b1 receptor respond to?

E = NE

25

What does b2 receptor respond to?

E

26

Catecholamines comes from what amino acid?

tyrosine

27

What is responsible for the liberation of DA (dopamine) and NE from the nerves vesicles?

Ca+2

28

In the ocular system an increase in IOP, risk in angle closure, and allergic reaction are adverse effects of what?

anticholinergics

29

The adverse effects of anticholinergics systematically are the ABCCDSS

Anorexia, Blur, Constipation & Confusion, Dryness, Sedation & Stasis of urine.

30

In the CNS (medulla) you get a decrease in Parkinson tremor and HR by this cycloplegic drug.

Anticholinergics