Lecture 5 Flashcards

1
Q

What is the role of the cytoskeleton?

A

To help maintain cell shape.

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2
Q

How does the cytoskeleton allow rapid changes in cell shape

A

This is due to the cytoskeletons ability to disassemble and reassemble.
The cytoskeleton is highly dynamic but still provides stability

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3
Q

What are the three main components that make up the cytoskeleton

A

Microtubules, Microfilaments, Intermediate filaments

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4
Q

What are microtubules composed of?

A

Tubulin subunits

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5
Q

What is the function of microtubules

A

Microtubules resist compression and thus help maintain cell shape

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6
Q

What is motility

A

the ability of an organism to move independently.

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7
Q

What kind of motion is flagella

A

Snake-like motion. eg. sperm cells

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8
Q

What kind of motion is cilia

A

rowing-like motion

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9
Q

How are microtubules also involved with organelle motility within the cell

A

Because ATP-powered motor proteins can walk organelles along microtubules.
This allows vesicles or other organelles to be transported to specific targets within the cell

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10
Q

What are microfilaments composed of

A

Microfilaments are a double chain of actin subunits

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11
Q

What do microfilaments form

A

They form linear strands and 3-dimenstional networks using branching proteins

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12
Q

What is the function of microfilaments

A

Microfilaments resist tension

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13
Q

How does the cortical network of Microfilaments (underneath the plasma membrane) help maintain cell shape

A

The dense cortical network makes the reigon less fluid, thus maintains cell shape

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14
Q

What are intermediate proteins made up of

A

Various proteins such as Keratins in the hair, lamins in the nucleus, neurofilaments in neurons

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15
Q

How are intermediate filaments structured

A

They are coiled into cables

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16
Q

What is the function of Intermediate filaments

A

They maintain cell shape and anchor organelles

17
Q

How come intermediate filaments are able to stay behind after the cell has died?

A

This is because intermediate filaments are relatively permanent cellular stuctures

18
Q

What are the three major types of cell junctions

A

Tight Junctions, Desmosomes, Gap junctions

19
Q

What is the function of tight junctions

A

They hold neighboring cells tightly pressed together
May form continuous seal
Prevents movement of fluid across cell layers

20
Q

What is the function of Desmosomes

A

They are an anchoring junction. They provide attatchments between sheets of cells eg. muscle

21
Q

When you have torn your muscle, what cell juction has been torn

A

You have a torn desmosome

22
Q

How are desmosomes connected into the cell

A

Desmosomes are connected into the cell by intermediate filaments.

23
Q

What is the function of Gap junctions

A

To allow ions and small molecules to pass from cell to cell.
This allows rapid intercellular communitcaion

24
Q

What are gap junctions

A

A point of cytoplasmic contact between two cells

25
What is ECM composed of
Material secreted by cells
26
By what process does secretion of ECM material occur
Constitutive Exocytosis
27
What are proteoglycans
Proteins with extensive sugar additions
28
What is the functions of proteoglycans in the EXM
Proteoglycans trap water. Water resists compression and thus helps retain tissue shape
29
What attatches the cells to the ECM
Fibronectins (these are glycoproteins)
30
What attaches the ECM to the cytoskeleton
Integrins
31
Define the ECM
The extracellular matrix (ECM) is the non-cellular part of tissues and is secreted via constitutive exocytosis