lecture 5 - cardiovascular system: introduction to CVS Flashcards

1
Q

why do we need a cardiovascular system?

A

exchange and transport of nutrients to maintain life

single cell organisms don’t need a specialised exchange system

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2
Q

functions of the CVS

A

controlled and continuous flow of blood

homeostasis

transport of hormones

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3
Q

organisation of the CVS

A

2 circulations in series served by 2 pumps in series

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4
Q

what are the 2 circulations in the CVS?

A

systemic
• high pressure, left, oxygenated
• supplies whole body

pulmonary
• low pressure, right, deoxygenated
• only supplies the lungs

each circulation receives the same volume of blood

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5
Q

what are the 2 chambers of the heart

A

atrium and ventricle

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6
Q

what are the 2 types of valves in the heart?

A

atrioventricular valves

semilunar valves

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7
Q

what are the 2 atrioventricular valves?

A
right = tricuspid 
left = mitral/bicuspid
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8
Q

what are the 2 semilunar valves?

A
right = pulmonary 
left = aortic
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9
Q

what causes the valves to open and close

A

pressure differences

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10
Q

what is stroke volume (SV)?

A

volume of blood pumped by 1 ventricle

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11
Q

what is cardiac output (CO)?

A

total volume of blood pumped per ventricle per minute

CO = HR x SV

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12
Q

what is venous return (VR)?

A

amount of blood returning to the heart

under steady state conditions VR = CO

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13
Q

what is the vascular system made of?

A

arteries
arterioles
capillaries
veins

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14
Q

arteries

A
  • high pressure
  • elastic
  • distribution
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15
Q

arterioles

A
  • high resistance
  • site for control of blood flow to tissues
  • surround by lots of vascular smooth muscle
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16
Q

capillaries

A
  • thin walled
  • exchange of materials
  • arranged in parallel
17
Q

veins

A
  • low pressure
  • capacitance
  • collection
  • 70% of blood is in the venous system at any time
18
Q

what is capacitance?

A

the ability of a system to store an electrical charge

in the veins

19
Q

what is blood flow driven by?

A

pressure gradient setup by the heart acting as a pump

energy is required to maintain the pressure gradient

20
Q

pressures in the vascular system

A

decreases from arteries to veins

greatest fall in pressure in the arterioles

pressure is pulsate in large arteries

systemic system > pulmonary system

21
Q

what is systolic pressure?

A
  • maximum pressure

* when contracting

22
Q

what is diastolic pressure?

A
  • minimum pressure

* relaxed and filling with blood

23
Q

what parameters determine the resistance?

A
  • length of the blood vessel
  • radius of the vessel
  • viscosity of blood
24
Q

equation for blood velocity

A

V = flow / XSA

XSA = cross sectional area

25
Q

how does blood velocity differ?

A

the higher the XSA the lower the velocity

velocity is lowest in the capillaries for efficient exchange