Lecture 59 - Endocrine 1 Flashcards

1
Q

Describe nervous system signaling

A

fast control via electrical signals

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2
Q

Describe endocrine system signaling

A

slower control via hormones in the blood

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3
Q

What physiological processes does the thalamus control

A
  1. hunger and thirst
  2. sleep-wake cycles
  3. emotional regulation
  4. autonomic nervous function (BP, HR, etc.)
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4
Q

what are the important structures of the anterior pituitary

A
  1. pars tuberalis
  2. pars intermedia
  3. pars distalis
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5
Q

Adenohypophysis

A

makes stimulating hormones in the anterior pituitary

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6
Q

what are the important structures of the posterior pituitary

A
  1. infundibulum
  2. pars nervosa
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7
Q

neurohypophysis

A

directly connects with the pars nervosa (posterior pituitary) via the infundibular stalk

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8
Q

the hypothalamus has a ______ connection to the anterior pituitary

A

vascular

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9
Q

the hypothalamus has a ____ connection to the posterior pituitary

A

neural

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10
Q

Using an H&E stain what cells are visible

A

acidophiles, basophils, and chromophobic cells

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11
Q

acidophils

A

site of growth hormone and prolactin synthesis

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12
Q

basophils

A

site of ACTH, TSH, LH, and FSH synthesis

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13
Q

chromophobes

A

resting state; no hormone synthesis

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14
Q

why does the pars nervosa appear washed out on stain

A

axons from the hypothalamus terminate in the posterior pituitary

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15
Q

T/F: hormonal signals are faster than nervous system transmission

A

FALSE

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16
Q

T/F: the hypothalamus connects to the posterior pituitary via a neural connection

17
Q

what hormones are produced in the hypothalamus

A

releasing hormones

ex: CRH, TRH

18
Q

what hormones are produced in the anterior pituitary

A

stimulating hormones

ex: ACTH, TSH

19
Q

what hormones are stored in the posterior pituitary

A

vasopressin and oxytocin

20
Q

what is the major function of oxytocin

A

smooth muscle contraction for parturition and lactation

21
Q

what are the major functions of vasopressin

A

water conservation (ANTI-diuretic)

22
Q

describe how vasopressin conserves water

A

osmoreceptors in the hypothalamus trigger release
has kidneys reabsorb water back into the blood

23
Q

How do central diabetes and nephrogenic diabetes differ in their vasopressin relationship

A

central diabetes is when insufficient vasopressin is made = dilute urine, polyuria

nephrogenic diabetes is when there is sufficient vasopressin but the kidneys do not respond = pyometra is a cause

24
Q

how does vasopressin regulate blood pressure

A
  1. vasoconstriction increases systemic vascular resistance
  2. released in response to hypovolemia and hypotension
25
give the hormone that is stimulated upon the release of: GnRH
LH, FSH
26
give the hormone that is stimulated upon the release of: PRH Dopamine
Prolactin (increases) Prolactin (decreases)
27
give the hormone that is stimulated upon the release of: CRH
ACTH
28
give the hormone that is stimulated upon the release of: TRH
TSH
29
give the hormone that is stimulated upon the release of: GHRH Somatostatin
growth hormone (increases) growth hormone (decreases)
30
match the structure to its associated hormone a. hypothalamus b. anterior pituitary c. target gland 1. stimulating hormone 2. hormone 3. releasing hormone
A = 3 B = 1 C = 2
31
The biological effect of a hormone is related to
its concentration in the blood
32
blood concentration of a hormone is determined by
the rate of secretion
33
negative feedback ____ whereas positive feedback ____
decreases; increases
34
which hormone produced by the posterior pituitary gland controls milk let-down in the lactating animal
oxytocin
35
CRH and GnRH are both examples of _____ hormones produced by the hypothalamus
releasing