Lecture 6 - Biomolecules Part 2 Flashcards

1
Q

What are proteins?

A

Large, complex molecules that do most of the work in cells

required for structure, function, and regulation of the body’s tissues and organs

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2
Q

Amino Acids

A

What proteins are made up of

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3
Q

How many types of amino acids are there that can be combined to make a protein?

A

20

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4
Q

Essential Amino Acids

A

Cannot be made in the body

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5
Q

Semi-Essential Amino Acids

A

Arginine and Histidine
Can be synthesized by adults but not kids

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6
Q

How are amino acids linked to form proteins?

A

Carboxyl and amino groups are synthesized through dehydration synthesis. Resulting compound has peptide bonds

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7
Q

Proteins shape is determined by:

A

The order that amino acids are joined in

Shape determines function

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8
Q

Dipeptide

A

2 amino acids linked by a peptide bond

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9
Q

Polypeptide

A

Many amino acids linked by peptide bonds

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10
Q

Protein structure:

A

One or more ploypeptides folded into a specific 3-dimensional shape

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11
Q

4 Levels of Protein Structure

A

Primary Structure
Secondary Structure
Tertiary Structure
Quaternary Structure

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12
Q

Primary Structure

A

Unique Sequence

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13
Q

Secondary Sequence

A

Hydrogen bonds between amino acids in the polypeptide

Parts of polypeptide coil or fold into a local pattern

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14
Q

Two types of secondary structures

A

Alpha Helix & Pleated Sheet

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15
Q

Tertiary Structure

A

Overall 3-dimensional shape of a folded polypeptide

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16
Q

Quaternary Structure

A

Only in proteins with two or more polypeptides

Overall shape after polypeptides fit together

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17
Q

Lysozyme

A

Antimicrobial enzyme produced by animals that forms part of the innate immune system

18
Q

Define Sickle Cell Hemoglobin

A

Sickled red blood cells are stiff and angular, causing them to become stuck in small capillaries

19
Q

Denaturation of Proteins

A

Process in which 3-dimensional shape of polypeptide becomes distorted

Protein no longer functions

20
Q

Causes of Denaturation

A

Temperature
PH
Salts

21
Q

Protein Functions

A
  1. Enzymatic
  2. Structural
  3. Contractile
  4. Defensive
  5. Transport
  6. Signaling
22
Q

Protein functions: Enzymes

A

Enzymes speed up chemical reactions

23
Q

Protein functions: Structural Proteins

A

Collagen - makes up bones, tendons, ligaments, skin

Keratin - Makes up hair, nails, claws, hooves, reptile scales

24
Q

Protein functions: Contractile proteins

A

Mediate sliding of contractile fibers (Muscles)

25
The two most important contractile proteins are called
Actin & Myosin
26
Protein functions: Defensive Proteins
fight off infections
27
Protein functions: Transport Proteins
act as doors to the cell
28
Protein functions: Signaling
interacts with and affects the behavior of neighboring cells
29
Two types of nucleic acids:
DNA RNA
30
DNA
Molecule that contains every organism's unique genes.
31
Nucleic acids are monomers or polymers?
Polymers
32
The monomers of nucleic acids are:
Nucleotides
33
The main difference between DNA and RNA nucleotides is:
Sugar RNA - Ribose DNA - Deoxyribose
34
Polynucleotides
Combination of nucleotide monomers which are connected through covalent bonds
35
DNA is _____ stranded
Double
36
RNA is ______ stranded
Single
37
Types of RNA involved in protein synthesis:
mRNA tRNA rRNA
38
mRNA:
messenger RNA, carries DNA message to ribosomes
39
tRNA:
Transfer RNA, transfers amino acids to ribosomes
40
rRNA:
Ribosomal RNA, makes up ribosome-protein factories of the cell