Lecture 7 Flashcards
1
Q
Capacitative Current
A
charges being loading onto the membrane capacitor
2
Q
Tetrodotoxin (TTX)
A
blocks voltage gated Na channels
From the pufferfish
3
Q
TEA
A
blocks K+ channels
4
Q
Early Current - Nav Current - What causes the U Shape?
A
- First, channel voltage sensors detect depolarization and activate channels
- Second, ball-and-chain inactivation quickly shuts the pore
5
Q
Late Current - K current
A
doesn’t show activation
K+ channels have no plug
6
Q
Na+ equilibrium potential (ENa)
A
The membrane voltage (Vm) at which the net current for Na+ is zero
