lecture 7/8

Question 1

A fibers

Answer 1

myelinated
sharp first pain
mech / therm stimulated

Question 2

C fibers

Answer 2

unmyelinated
poorly localized
mech/ther/chemical

Question 3

where do A delta and C fibres synapse

Answer 3

posterior horn

Question 4

where is first site of pain modulation

Answer 4

posterior horn

Question 5

nociceptor specific neurons receive input from ____ and ____ they are specific for ____

Answer 5

C
A
pain

Question 6

wide dynamic range neurons receive input from __ and __ and ___

Answer 6

AB fibers, C and A

Question 7

interneurons receive __ input and play a role in ___

Answer 7

diverse

pain modulation

Question 8

WDR can fire __ in ___ fashion

Answer 8

AP

graded

Question 9

WDR and dependent on __ singling

Answer 9

C

Question 10

T/F WDR can wind up and lead to sensitization

Answer 10

true

Question 11

the amplification system that responds to __ fibres

Answer 11

wind up

C

Question 12

wind up is a __ in threshold and ___ in sensitivity

Answer 12

reduction

increase

Question 13

wind up priority ___

Answer 13

saliency

Question 14

anterolateral system compromises fibres of ____ and ___ from SC to ___ and ___

Answer 14

pain / temp

brainstem / thalamus

Question 15

tract that compromises only the fibres projecting from SC to thalamus

Answer 15

spinothalamic

Question 16

medial system

Answer 16

affective motivational component
ouch
suffering

Question 17

lateral system

Answer 17

discriminative localized

pain in left toe

Question 18

medial system area of brain

Answer 18

anterior cingulate cortex

Question 19

lateral system area of brain

Answer 19

primary somatosensory

Question 20

chronic pain

Answer 20

chronic: inflammatory pain
neuropathic
idiopathic

Question 21

example chronic inflatmmory pain

Answer 21

arthritis

Question 22

example chronic neuropathic pain

Answer 22

postherpetic neuralgia

Question 23

example idiopathic pain

Answer 23

fibromyalgia

Question 24

maladaptive mechanisms

Answer 24

peripheral

central

Question 25

peripheral maladaptive mechanisms

Answer 25

sensitazation over expression of receptors

Question 26

central maladaptive mechanisms

Answer 26

wind up, changes in neurotransmitter receprots | disinhibition

Question 27

central sensitization types

Answer 27

para dys hyper allodynia

Question 28

parethisia / dysesthesias

Answer 28

increased spontaneous activity

Question 29

hyperalgesia

Answer 29

reduced threshold for pain

Question 30

allodynia

Answer 30

non noxious stimuli interpreted as painful

Question 31

neuropathic pain symptoms

Answer 31

burning shooting electrical

Question 32

nociceptive pain

Answer 32

squeeze throbbing aching

Question 33

__ and __ fibres influence gut mobility

Answer 33

sympathetic and parasymp.

Question 34

sensory information from the gut comes from what two sources

Answer 34

``` parsympatethic fibers (physiological - full) sympathies fibers (pain) ```

Question 35

T/F referred pain can be from visceral nerve to somatic area

Answer 35

true

Question 36

T/F referred pain can be from somatic nerve to somatic area

Answer 36

T

Question 37

what innervates diaphragm

Answer 37

phrenic

Question 38

cortical areas of limbic system

Answer 38

cingulate gyrus parahippcampal uncut

Question 39

subcortical structures of limbic system

Answer 39

amygdala | hippocampus

Question 40

hippocampus respsonsibel for

Answer 40

memory learning viceral / endocrine function emotional behaviour

Question 41

types of memory

Answer 41

declarative / explcit | non declarative / implicit

Question 42

types of declarative / explicit memory

Answer 42

episodic (events) | semantic (factors

Question 43

Decartlive / explicit memories what brain area

Answer 43

hippocampus | cortical

Question 44

types of non declarative implicit memories

Answer 44

skills habits emotioanl memory

Question 45

brain for non declarative implicit memory

Answer 45

basal ganglia cerebllum Amy cortical areas

Question 46

Case of HM

Answer 46

bi lateral hippocampus lesion loss of recent memory intelligence not affected

Question 47

____ memory system for delclartive memory

Answer 47

medial temporal lobe

Question 48

basic papez circuit

Answer 48

cingulate cortex hippocampus mamm body thalamaus

Question 49

Amygala

Answer 49

emotional memories fear reward motivation what important

Question 50

Case of Sm

Answer 50

bilateral Amy lesion | absesne sense of fear

Question 51

emotional attention

Answer 51

reflective system (involuntary / automated)

Question 52

Dopamine associated with wanting or liking

Answer 52

wanting

Question 53

addiction activation of ___

Answer 53

dopamine neurons from VTA