Lecture 77 - Intro to Human Virology

Question 1

_______ is the term that describes the glycoproteins found inserted into and sticking off of viral envelopes.

Answer 1

Peplomer

Question 2

_____ protein is the protein located between the capsid and the envelope (not found in all enveloped viruses.)

Answer 2

Matrix

Question 3

____ capsids are sometimes referred to as nucleocapsids. The capsomeres attach directly to the Nucleic acid of the virus. All of these types of viruses we will discuss will have envelopes.

Answer 3

Helical capsids

Question 4

____ cell cultures are derived from tissues and can only grow for a limited number of generations. They can be mixed cultures.

Answer 4

Primary

Question 5

______ cell cultures are derived from normal human tissue and are fibroblast or epithelial like. They maintain a ______ complement of chromosomes and can be immortalized.

Answer 5

Diploid

Diploid

Question 6

_____ _____ cell cultures are often derived from tumors, so they are immortalized, and they are often aneuploid.

Answer 6

Continuous line

Question 7

Of the components of the MMR vaccine, which are grown in eggs and which are grown in cell culture?

Answer 7

MM grown in eggs

R grown in cell culture

Question 8

Do biological or physical methods of viral diagnostics measure infectious virus? Which one measures viral components?

Answer 8

Biological measures infectious virus.

Physical measures viral components.

Question 9

____ ____ ____ (DFA) testing is a physical method of diagnostics. It is rapid, with very high ______ but low ______ (so positive is almost certain, but negative is not conclusive).

Answer 9

Direct Immunofluorescence

Specificity

Sensitivity

Question 10

________ inhibition assay is used to diagnose orthomixaviridae (influenza is in this family.) RBCs + virus results in ________, but adding Ab that recognizes the virus prevents this reaction. This is a good way to identify flu strains.

Answer 10

Hemagglutinin

Hemagglutination