Lecture 8 Parental Development Flashcards

(60 cards)

1
Q

What is the period of the zygote (blastocyst) phase?

A

0–14 days:
ball‑like structure of 60–80 cells by day 4,
implantation occurs between days 8–14.

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2
Q

What happens to fertilized ova during implantation?

A

Only half implant firmly; of these, half are genetically abnormal or fail to develop; ~¾ of zygotes fail this phase.

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3
Q

How do identical (monozygotic) twins form?

A

Splitting of the inner cell mass of the blastocyst, can occur before or after implantation.

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4
Q

How do fraternal (dizygotic) twins form?

A

When two separate eggs are released and both are fertilized.

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5
Q

What marks the transition to the embryonic period?

A

Blastocyst implants in uterine wall and becomes an embryo (3–8 weeks).

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6
Q

What are the two developmental patterns during embryo development?

A

Cephalocaudal (head→tail) and proximodistal (centre→periphery).

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7
Q

What develops by week 3 of embryonic stage?

A

Head, tail, brain, circulatory system begin; heart starts beating.

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8
Q

What is fetal development by week 4?

A

Embryo ~2 cm; spinal cord, arms, legs, digestive and nervous systems form; brain differentiates.

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9
Q

What occurs during weeks 5–7 of the embryo?

A

Week 5: hands & lungs begin;
Week 6: head grows, limbs form;
Week 7: muscles form, cerebral cortex begins.

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10
Q

What is the function of the amnion?

A

A watertight sac with fluid that cushions, regulates temperature, provides weightless environment.

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11
Q

What is the chorion?

A

Membrane surrounding amnion; later becomes the placenta lining.

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12
Q

What does the allantois form?

A

The umbilical cord.

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13
Q

What is the role of the placenta?

A

Transports oxygen and nutrients from mother; removes waste from embryo; filters some toxins.

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14
Q

What are the umbilical cord’s components?

A

Three blood vessels: one brings nutrients to embryo, two remove waste.

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15
Q

What forms by the end of the 8th embryonic week?

A

at about 8 weeks, the embryo develops its first bone cells which mark the end of the differentiation into the major structures.

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16
Q

What is the neural tube?

A

Fused ectodermal groove that develops into the brain and spinal cord.

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17
Q

When do first bone cells appear in the embryo?

A

Around 8 weeks—marks end of major structure differentiation.

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18
Q

When does the fetal period begin and what characterizes it?

A

9th week to birth: growth, fine feature development (fingernails, eyelids, eyebrows).

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19
Q

When can fetal reflexes and heartbeat be detected?

A

By 12 weeks (~7.5 cm): response to touch (grasp, Babinski, suck reflex); heartbeat audible.

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20
Q

When does spontaneous movement start in fetus?

A

Around 5–6 weeks; by 12 weeks, most neonatal movements are present.

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21
Q

What sensory stimuli does the fetus receive?

A

Tactile, taste (amniotic fluid flavours), smell (odor transfer), limited sight, and hearing.

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22
Q

What is the fetal hearing environment like?

A

Noisy – 70–95 dB (like a lawnmower); fetus responds to maternal voice (heart rate changes).

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23
Q

When does fetal learning begin?

A

Last 3 months of pregnancy: CNS supports habituation, preference for familiar stimuli.

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24
Q

What is fetal habituation?

A

Decreased response to repeated stimulation; heart rate studies show novelty response.

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25
What reflexes indicate fetal learning?
Fetal heart rate increases when hearing familiar voice (e.g., mother reading).
26
What are teratogens?
External agents (drugs, diseases, chemicals, radiation) that damage or kill prenatal organisms.
27
Why is the first trimester critical for teratogen impact?
Disruption during critical embryonic/early fetal development often causes miscarriage or serious defects.
28
What are examples of drug-related teratogens?
Alcohol, heroin, cocaine, tobacco – lead to FASD, low birth weight, cognitive deficits.
29
What is Fetal Alcohol Spectrum Disorder (FASD)?
Causes small head, brain damage, facial/joint malformations, behavioural issues (irritability, hyperactivity, seizures).
30
What were effects of thalidomide exposure?
Missing or malformed limbs, deafness, facial deformities, seizures, dwarfism, brain damage.
31
What is the effect of prenatal rubella infection?
High risk of deafness, blindness, birth defects—especially if infection during week 8 (~60‑85% risk).
32
What is phylogenetic continuity?
The principle that humans share traits with other animals due to common evolutionary ancestry.
33
How is prenatal development divided?
Three phases: zygote (0–14 d), embryo (3–8 w), fetus (9 w–birth).
34
What are the differences between mitosis and meiosis?
Mitosis: one division → two identical diploids; Meiosis: two divisions → four unique haploids.
35
What are key fetal capabilities?
Movement, reflexes, sensory reception, and early learning.
36
What is the summary of teratogen impact period?
Exposure in the first trimester carries highest risk of miscarriage or major birth defects.
37
What is phylogenetic continuity?
The idea that humans share many characteristics with other animals due to common evolutionary origins.
38
What is the aim of this lecture on prenatal development?
To introduce the processes of prenatal development, fetal learning, and hazards to fetal development.
39
What are gametes?
Sex cells (sperm and ova) that are haploid and contain 23 chromosomes.
40
Are gametes haploid or diploid?
Haploid – they contain only one set of chromosomes (23).
41
What does diploid mean?
A cell that contains two sets of chromosomes (46 total), one from each parent.
42
What is meiosis?
A type of cell division that reduces chromosome number by half and leads to the production of gametes.
43
What happens in Prophase I of meiosis?
**Crossing over or recombination of chromosomal materia**l between the homologous chromosomes. This reshuffling creates new hereditary combinations and recombinations. The process facilitates genetic variability as each egg and sperm **After recombination, the chromosomes are no longer identical to those inherited from the parents**
44
What are the products of meiosis?
Four haploid cells, each genetically unique.
45
What is the site of conception?
Fallopian tubes.
46
What happens when the sperm penetrates the ovum?
A chemical reaction prevents other sperm from entering, the tail falls off, and the nuclei of sperm and egg fuse.
47
What is a zygote?
A fertilized egg formed by the union of sperm and ovum.
48
What are the three phases of prenatal development?
1) Zygote (0–14 days), 2) Embryo (3–8 weeks), 3) Fetus (9 weeks to birth)
49
What is the period of the zygote?
0–14 days; from conception to implantation in the uterus.
50
What is the period of the embryo?
3–8 weeks; major organs begin to form.
51
What is the period of the fetus?
9th week to birth; organs function and growth occurs.
52
What is a blastocyst?
A hollow ball of cells resulting from mitosis of the zygote; implants into the uterus.
53
What are the three layers of the blastocyst?
Ectoderm, mesoderm, and endoderm.
54
What does the ectoderm develop into?
Skin, hair, nails, sensory organs, and nervous system.
55
What does the mesoderm develop into?
Muscles, bones, inner skin, circulatory, and excretory systems.
56
What does the endoderm develop into?
Digestive system, liver, pancreas, salivary glands, and respiratory system.
57
What other structures are formed from the blastocyst?
Placenta, umbilical cord, and amniotic sac.
58
What is mitosis?
A process of cell division that results in **two identical diploid cells** for **growth and repair**.
59
Meiosis vs Mitosis - What is the key difference?
Meiosis produces four genetically unique haploid gametes; mitosis produces two identical diploid cells.
60
What is the function of recombination during meiosis?
It increases genetic diversity by creating new combinations of alleles.