Lecturio quiz questions

Question 1

Which type of cell is the characteristic histologic feature of Hodgkin’s lymphoma?

Answer 1

Reed-Sternberg cells

Question 2

What is the function of The regulatory protein BCL2?

Answer 2

Inhibit Apoptosis

Question 3

What is the most common type of non-Hodgkin lymphoma?

Answer 3

Diffuse large B-cell lymphoma

Question 4

What histological feature is seen in Burkitt lymphoma?

Answer 4

Starry sky

Question 5

To which of the following body parts is lymphoblastic lymphoma more likely to metastasize?

Answer 5

Testicles

Question 6

Which of the following cells are most often associated with chronic lymphocytic leukemia?

Answer 6

Smudge Cells

Question 7

which white blood cells respond in the acute phase of inflammation?
Neutrophils
Basophils
Lymphocytes
Monocytes

Answer 7

neutrophils

Question 8

How might the nurse be able to tell the difference between a viral infection and a bacterial infection through the results of a complete blood count (CBC)?

Answer 8

Neutrophils are elevated in bacterial infections, and lymphocytes are elevated in viral infections.

Question 9

What is likely to occur in a client’s WBCs if the client is infected with human immunodeficiency virus (HIV)?

Answer 9

Lymphocytopenia

Question 10

What is expected to occur to the hematocrit level collected from a dehydrated client?

Answer 10

Hematocrit levels will rise

Question 11

How much is each unit of packed red blood cells (PRBCs) expected to raise the hematocrit level?

Answer 11

~3%

Question 12

Which component of a complete blood count (CBC) is used to help diagnose the type, cause, and severity of an anemia?

Answer 12

MCHC

Question 13

What can cause a decrease to both the mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH)?

Answer 13

Anemia of chronic disease

Question 14

Which component of the red blood cell count is most affected by the client’s hydration status?

Answer 14

Hematocrit

Question 15

An important mediator of primary hemostasis is…

Answer 15

…von Willebrand factor.

Question 16

What is the end product of the coagulation cascade?

Answer 16

Fibrin

Question 17

What factor activates the extrinsic pathway?

Answer 17

Tissue factor

Question 18

What principally drives the coagulation cascade after an injury?

Answer 18

Extrinsic pathway

Question 19

Thrombin cleaves which of the following factors?

Answer 19

V, VIII, XIII

5, 8, 13

Question 20

Thrombin is necessary for which of the following events?

Answer 20

Endothelial activation

Question 21

What factor do the endothelial cells synthesize?

Answer 21

VIII (8)

Question 22

What is the function of the heparin-like molecule?

Answer 22

Inhibits Thrombin

Question 23

Thrombomodulin acts as a…

Answer 23

Coagulation inhibitor

Question 24

What substances play an essential role in the extrinsic pathway?

Answer 24

Ca ions and factor 7a

Question 25

Antithrombin III activity is enhanced by...

Answer 25

Heparin

Question 26

What cleaves the fibrin clot?

Answer 26

Plasmin

Question 27

Thrombolysis results in the formation of...

Answer 27

...fibrin degradation products.

Question 28

Fibrin degradation products are important prognostic indicators of what condition?

Answer 28

Pulmonary Embolism

Question 29

Coagulation factors assemble on the phospholipid surface of what substance?

Answer 29

Platelets

Question 30

What test helps to diagnose a disease that causes uncontrollable clotting?

Answer 30

D-dimer

Question 31

Platelet dysfunction and decreased platelet aggregation may be caused by which of the following?

Answer 31

NSAIDs

Question 32

PTT is particularly useful to measure which of the following?

Answer 32

Intrensic pathway

Question 33

PTT has to be monitored in patients who are on which drug?

Answer 33

Heparin

Question 34

Which of the following is found in higher amounts in beta-thalassemia major?

Answer 34

Hb F

Question 35

Which of the following conditions will result in a mild increase in HbA2, mild decrease in HbA1, a normal fetal hemoglobin, and absent Hb H on electrophoresis ?

Answer 35

Beta-thalassemia trait

Question 36

What is the common complication of treatment of thalassemia?

Answer 36

Iron Overload

Question 37

Which of the following does NOT cause a decrease in red blood cell production? Aplastic anemia Polycythemia Vera Carcinoma infiltration Myeloproliferative disease Leukemia

Answer 37

Polycythemia Vera

Question 38

Which red cell mass and plasma volume would you expect in a patient with primary polycythemia?

Answer 38

Increased Red cell mass and normal plasma volume

Question 39

Which gene is commonly associated with polycythemia vera?

Answer 39

JAK 2

Question 40

What cell types are predominantly involved in acute leukemia?

Answer 40

Early hemopoietic progenitor cells

Question 41

Which of the following cells is is seen in myeloid leukemia on a bone marrow aspirate?

Answer 41

Primitive myeloblasts

Question 42

what is the most common presentation of chronic lymphoid leukemia?

Answer 42

Elevated lymphocites noted on labs ordered for other reasons

Question 43

Which B-cell receptor signalling pathway is blocked in order to inhibit the proliferation signals produced by tumor cells?

Answer 43

BTK (Burton's kinases)

Question 44

Which of the following is a characteristic feature of the blood smear in chronic lymphocytic leukemia?

Answer 44

Smudge Cells

Question 45

The characteristic feature is the presence of what kind of cells in Hodgkin lymphoma

Answer 45

Reed Sternberg cells

Question 46

Which of the following viruses is implicated in a subset of cases of Hodgkin lymphoma?

Answer 46

EBV

Question 47

Which of the following is required to make a definitive diagnosis of Hodgkin lymphoma?

Answer 47

Biopsy of affected tissue