Lesson 10 - Dyslipoproteins

Question 1

Type I

Answer 1

Hyper-Chylomicronemia (low levels lipase for lipoprotein or low Apo C-II

Question 2

Type II - a

Answer 2

Hyper-Cholesterolenmia without Hyper-TG

Question 3

Type II-b

Answer 3

Hyper-Cholesterolemia With Hyper-TG

Question 4

Type III

Answer 4

Apo-E problem.. IDL affected

Question 5

Type IV

Answer 5

Hyper-TG without Chylomicrons

Question 6

Type V

Answer 6

Hyper-TG With Chylomicrons

Question 7

Hyper-Lipidemia

Answer 7

Inc Cholest / TG
It can also determine Hyper-Lipoprtenemia
Primary = No underlying condition
2ndary = Manifestation of other problem

Question 8

Metabolic Syndrome

Answer 8

Mix of risk factors with metabolic origin
Increase risk of atherosclerotic CVD
Seen with insulin resistance

Question 9

Fam. Hyper-Chylomicronemia

Answer 9

Inc T.G >1000mg/dL due to chylomicronemia

Dec clearance of chylomicrons = Dec lipase

Question 10

Fam. Lipoprotenimia Lipase defiency

Answer 10

Hyper- TG causes dec LPL
VLDL [ ] =  normal 
but HDL and LDL = dec.
Apo C-II = normal
Decrease cholesterol = not a good thing... because you need it to make hormones.

Question 11

Fam. Hyper-TG

Answer 11

Inc T.G due to Lg VLDL - Polygenic ori.

Seen in diabetic/Obese/Hypertension/CVD

Question 12

Hyperprotenemia & HyperLipoprotenemia

Answer 12

Dec. Na+ in pseudohyponatremia (lesson 3)

Question 13

Fam. Hyper-Cholesterolemia

Answer 13

Inc. LDL [ ] due to Inc. LDL , the liver tissue will use

Scavenger-R will take all the oxidized LDL and form Foam cells.. due to eaten up by macrophages