Lesson 13: Making Changes after You Receive Approval

Question 1

Once you receive IACUC approval, make sure that you?

Answer 1

submit an amendment to your protocol before making any significant changes in your animal procedures.

Question 2

What is considered a significant change?

Answer 2

*Drug dosage changes
*Increasing the number of animals used
*Addition of new drugs/agents
*Performing an additional procedure such as adding another time point for blood collection
*Using animals approved for use on one of your protocols for use on another of your IACUC-approved protocols.