Leucemia aguda Flashcards

1
Q

Analítica de leucemia aguda

A

Más de 20% de blastos

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2
Q

Características LAM M3 o promielocítica

A

t(15,17) –> PML RARalfa
Bastones de Auer
Tto ATRA + ATO
Complicación –> CID

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3
Q

Leucemia relacionada con VEB

A

LAL-L3

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4
Q

Leucemia + HTLV1

A

LAL-T

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5
Q

Factores pronósticos LAM

A

Buen px: t(15,17) –> M3; inv16 –> M4Eo; t(8,21) –> M2; NPM

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6
Q

Características LAM

A

Mayores, MPO +
Tto inducción ARA-c + antraciclinas
Tto postinducción: QT si buen px, TPH si mal px

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7
Q

Características LAL

A

InfantiL, invaden sistema nervioso centraL –> profilaxis intratecaL (MTX + ARA-CC + CE)
Tratamieto inducción vincristina y postinducción con QT 2-3 años

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8
Q

Factores pronósticos LAL

A

Buen px –> PRE-B, CALLA +, hiperdiploidía
Mal px –> Filadelfia

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