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Hemato MIR > Mieloma múltiple > Flashcards

Mieloma múltiple Flashcards

1
Q

Clínica típica mieloma múltiple

A

Calcio sérico elevado
Riñón
Anemia normo-normo
Bones (dolor óseo)

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2
Q

Clínica renal MM por orden de frecuencia

A

1) Riñón de mieloma –> Proteinuria de Bence Jones ELEVADA (TCD y TC)
2) Hipercalcemia
3) Otros: cadenas ligeras, Fanconi secundario, amiloidosis primaria (AL)

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3
Q

Diagnóstico MM

A

Biopsia de MO (más de 10% células plasmáticas) + proteinograma en orina y/o suero (pico monoclonal) + Síntomas

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4
Q

Tratamiento MM

A

SOLO si síntomas –> Melfalán + CE + daratumumab + Bortezomib O lenalidomida
Plantear asociar TPH auto después si menores de 70 años

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5
Q

Factores pronósticos MM

A

Respuesta a tto (+ IMPORTANTE)
Fracaso renal
Edad
b2 microglobulina
Albúmina

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6
Q

Tratamiento anti CD38 (MM)

A

DARATUMUMAB

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7
Q

Proteinuria de Bence Jones

A

Riñón de mieloma

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8
Q

Clínica más frecuente en MM

A

Dolor óseo

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Hemato MIR (9 decks)

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