Lipids Flashcards

1
Q

What are lipids?

A

Heterogeneous compounds that are not readily soluble in water or polar solvents but are readily soluble in organic solvents such as chloroform, hydrocarbons, etc.

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2
Q

Most common Lipids in nature?

A

Fatty acids linked by ester bonds to glycerol or other alcohol such as cholesterol

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3
Q

Lipids have the same solubility property?

T/F

A

T

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4
Q

How are lipids classified?

A

Into three groups based on the number and types of components present in the lipid.

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5
Q

What are the classes of lipids?

A

Primary lipids

Derived lipids

Compound lipids

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6
Q

What are simple lipids?

A

They are the simplest form of lipids and the esters of fatty acids with various types of alcohols.

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7
Q

What products do simple lipids yield when hydrolyzed?

A

Two products:

Alcohol or glycerol & fatty acids

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8
Q

Why are fats solid at room temperature?

A

Due to the presence of saturated fatty acids (no double bond).

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9
Q

What are sphingophospholipids made up of?

A

Sphingosine, fatty acids, phosphoric acid & choline.

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10
Q

What are complex/compound lipids?

A

These are lipids that yield 3 or more products upon hydrolysis. They contain other amphipathic compounds together with the fatty acids and alcohol present in simple lipids.

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11
Q

Why are oils liquid at room temperature?

A

Die to the presence of unsaturated fatty acids.

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12
Q

Where is fat stored in animals?

A

White adipose tissue or fatty tissue

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13
Q

Why are wax solid at room temperature?

A

Due to presence of saturated fatty acids and high molecular weight monohydric alcohol.

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14
Q

Examples of complex/compound lipids

A

Phospholipid
Glycolipids
Lipoprotein
Sphingolipid
Sulpholipid

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15
Q

What are derived lipids?

A

These are lipids derived from the hydrolysis of simple and complex lipids.

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16
Q

Examples of derived lipids

A

Fatty acids, glycerol, steroids, sterol

17
Q

The most common fatty acids in humans

A

Stearic acid (C18) palmitic acid (C16) myristic acid (C14)

18
Q

Examples of simple lipids

A

Fat, oil, wax

19
Q

Define wax

A

Wax is a simple lipid that is solid at room temperature due to the presence of saturated fatty acid chain and a high molecular weight monohydric alcohol.

20
Q

Double bonds in PUFA are usually separated by?

A

Methylene group (CH2)

21
Q

PUFA are FA obtained from?

A

Plant seeds

22
Q

Which of the PUFA is omega 6 and why?

A

Linoleic acid. Because its last double bond is on carbon 6 counting from the omega (methyl) end of the FA chain.

23
Q

What is the code name for oleic acid?

A

18:1;9

24
Q

What is the code name for linolenic acid?

A

18:3;9,12,15

25
Q

Examples of MUFA

A

Palmetoleic acid
Oleic acid

26
Q

Symptoms of EFA deficiency

A

Dermatitis & hair loss
Depression
Infertility
Growth retardation
Poor wound healing
Kidney & liver disease

27
Q

The most noticeable deficiency of EFA is?

A

Skin disorders such as scaly dermatitis

28
Q

What is the code for omega 6 fatty acid

A

18:2;9,12

29
Q

What are eicosanoids

A

Eicosanoids are a complex family of bioactive lipid messengers, generated by oxygenation of 20C PUFA, primarily arachidonic acid.

30
Q

Classes of eicosanoids

A

Prostanoids (ring structure)

Linear eicosanoids

31
Q

Examples of eicosanoids with ring structure

A

Prostaglandin

Prostacyclin

Thrombaxanes

32
Q

Examples of linear eicosanoids

A

Leukotrienes

Lipoxins

Hydroxyl eicosatetraenoid acid (HETE)

33
Q

What do prostaglandins do in the human body

A

Help regulate physiological functions like blood pressure, contraction of uterus, inflammatory signals.

34
Q

Code name for arachidonic acid

A

C20: 4; 5, 8, 11, 14