Lipoprotein Metabolism Flashcards
The highest phospholipids content is found in
HDL
The class of lipoproteins that is protective against atherosclerosis is
HDL
Genetic deficiency of lipoprotein lipase cause hyperlipoproteinemia of the following type
Type IIa
Activated lecithin cholesterol acyltransferase is essential for the conversion of
HDL 3 to HDL 2
Zellweger’s syndrome is associated with abnormality of
Essential fatty acid metabolism
Tangier disease is a disorder of lipoprotein metabolism. The phenotype corresponds to
Low level of HDL
Although ketogenesis occurs in hepatocytes, it cannot utilise ketone bodies. It is due to a deficiency of which enzyme?
Thiophorase
Fatty acid oxidation is regulated by malonyl CoA. The malonyl CoA inhibits
Shuttling of fatty acyl CoA to mitochondria
Familial hypercholestorolemia is a codominant genetic disorder caused by a mutation of the gene that encodes for
LDL receptor
Which is an integral apolipoprotein present in a chylomicron?
Apo B48
Which is an integral apolipoprotein present in VLDL, IDL and LDL?
Apo B100
Which apolipoprotein that is present in chylomicron serves as the activator of an enzyme lipoprotein lipase LPL?
Apo CII
Chylomicron remnants are rapidly taken by the liver in a process that needs
Apo E
The clearance of LDL cholesterols in hepatocytes needs
LDL receptor
The HDL is taken up by hepatocytes via
Scavenger receptor B1
