Liver Function Flashcards
Hepatic artery provides __% of the total blood supply to the liver while portal vein provides __%.
25%, 75%
Liver cells that line the sinusoids which are capable of engulfing bacteria, debris, and toxins
Kupffer cells
Type of jaundice that yields a gray-colored stool and increased conjugated bilirubin
Post-hepatic jaundice
Inherited disturbance of bilirubin metabolism caused by a genetic deficiency of UDPGT
Criggler Najjar Syndrome
Intermittent unconjugated hyperbilirubinemia in the absence of hemolysis and underlying liver disease due to a defective conjugation system
Gilbert’s Syndrome
Deficiency of canalicular multidrug resistance/multispecific organic anionic transporter protein (MDR2/cMOAT); obstructive hyperbilirubinemia
Dubin-Johnson Syndrome
Conjugated hyperbilirubinemia due to a defective excretion; idiopathic
Rotor’s Syndrome
Enzymes involved in the elimination of alcohol by the liver
Alcohol dehydrogenase and acetaldehyde
Total protein and A/G ratio are tests done to check what function of the liver?
Synthetic
What test determines the liver’s detoxifying function?
Quick’s or Hippuric Acid Test
Which fraction of bilirubin is increased in physiologic jaundice of the newborn?
Unconjugated
Physiologic jaundice among infants is caused by deficiency of which enzymes?
Glucoronyl transferase and UDPGT
___% of the daily production of cholesterol is produced by the liver.
70
Jaundice becomes noticeable to the eye once bilirubin levels reach ___mg/dL.
> 3.0
Defined as the deposition of bilirubin in the brain; common among infants with Crigler-Najjjar syndrome
Kernicterus
