Liver Histology

Question 1

Glisson’s capsule

Answer 1

fibrous capsule surrounding liver

Question 2

Shape of hepatocytes

Answer 2

hexagons

Question 3

Center of hepatocytes

Answer 3

central vein

Question 4

Corners of hepatocytes

Answer 4

portal canal

artery, bile duct, vein, lymph

Question 5

Bile duct endothelium type

Answer 5

simple cuboidal

Question 6

Spaces between lines of hepatocytes

Answer 6

sinusoids

Question 7

Hepatocytes nucleation status

Answer 7

often binucleate

Question 8

Microvilli in space of Disse

Answer 8

help hepatocytes absorb things

Question 9

Capillary type in liver

Answer 9

fenestrated

Question 10

Blood flow in hepatocyte

Answer 10

portal canal –> central vein

Question 11

Bile flow in hepatocyte

Answer 11

middle (central vein area) –> portal canal

Question 12

Stellate cells

Answer 12

store vitamin A

become fibrogenic –> cirrhosis

Question 13

Bile accumulates outside of hepatocytes into

Answer 13

bile canaliculi

Question 14

Portal lobule concept

Answer 14

triangle formed by 3 central veins

center = portal canal

Question 15

Classic liver lobule concept

Answer 15

hexagon
central vein at center
corners = portal canals

Question 16

Acinus lobule concept

Answer 16

center is terminal branch of portal vein or hepatic artery
Zone 1: closest to vessels
Zone 2: middle
Zone 3: closest to central vein

Question 17

Acinus lobule concept

zones

Answer 17

Zone 1: closest to vessels
Zone 2: middle
Zone 3: closest to central vein