Viral Hepatitis

Question 1

Classes of hepatitis viruses
HAV
HBV
HCV
HDV
HEV

Answer 1

A: IV
B: VII
C: IV
D: V

Question 2

Which hep infections are only acute?

Answer 2

A and E

Question 3

Hep D requires

Answer 3

hep B infection already present

Question 4

Hep A and E transmission

Answer 4

fecal-oral

shedding in stool

Question 5

Hep B, C, D transmission

Answer 5

blood/bodily fluids

viremia

Question 6

Hep E is really bad in this population

Answer 6

pregnant women

Question 7

Expectant mothers have really bad reaction to this hep

Answer 7

hep E
E = expectant
*esp in 3rd trimester

Question 8

Why can Hep D only infect in setting of Hep B?

Answer 8

requires hep B for enveloped

Question 9

Test for acute Hep A

Answer 9

anti-HAV IgM

Question 10

HBV: preferred infection course

Answer 10

acute

says you’re clearing the infection

Question 11

3 antigens in HBV

Answer 11

c: core antigen
e: secreted into blood w/ replication
s: surface antigen

Question 12

Serology for HBV

Answer 12

HBsAg
then anti-Hbs Ab
between may be a “window” where both tests are negative but the patient is really still infected
need to retest months apart

Question 13

cccDNA

Answer 13

covalently circular closed DNA

in HBV