Liver Part 2 Flashcards

1
Q

Viral hepatitis can lead to (3)

A

Portal hypertension
Cirrhosis
Hepatocellular carcinoma

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2
Q

How is Hep a spread

A

Fecal oral route

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3
Q

Hep a is epidemic in developing countries affecting

A

THE YOUth

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4
Q

Hep a is a _____ infection

A

Acute

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5
Q

Hep a causes death by

A

ACUTE LIVER FAILURE

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6
Q

Hep B is transmitted

A

Parenterally but also from blood

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7
Q

Where is hep c a major health problem

A

Italy and mediterranean

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8
Q

Hep c spreads throug h

A

Blood

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9
Q

Hep C is detected in lab tests by

A

Presence of antibodies

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10
Q

Hep D is dependent on

A

Having Hep B first

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11
Q

Geographically hep D is where

A

Same as hep B

uncommon in NA

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12
Q

Hep D is common in what type of people

A

IV drug users

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13
Q

Sign of viral hepatitis

A

Jaundice

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14
Q

7 symptoms of viral hep

A

Fatigue, headache, anorexia, fever, abdominal pain, nausea and vomiting

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15
Q

Acute hepatitis implies recovery within ____ months

A

4

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16
Q

Acute hepatitis shows the parenchyma as more _______ leading to the appearance of _____________ ______ Walls

A

Hypoechoic

Bright periportal

17
Q

Sonographic appearance of Acute hepatitis is

A

Starry night sign

18
Q

Chronic hep biochemical abnormalities persist beyond

19
Q

Chronic hep will show have ________ present in tests

A

Antibodies

20
Q

On sonogaphy we will see _____ and ______ with Chronic hep

A

Hepatomegaly & thickening of GB wall

21
Q

Can Liver appear normal with Chronic hep

22
Q

Chemicals that are harmful to liver (2)

A

Alcohol

Presecription meds

23
Q

4 disorders of liver metabolism

A

Steatosis (fatty liver)
Glycogen storage disease- neonatal
Cirrhosis- chronic liver disease
NASH- non-alcoholic steatohepatitis

24
Q

Steatosis (fatty liver) is a ______ and _____ disorder of metabolism

A

Acquired and reversible

25
Steatosis (fatty liver) is most common cause of _____ recent increase
Obesity
26
Steatosis (fatty liver) affects the _____ in the hepatocytes
Triglycerides (fat)
27
10 causes of Steatosis (fatty liver)
``` Excessive alcohol —> causes lipolysis Severe hepatitis Hyperlipidemia (cholesterol) Diabetes Excess corticosteroids Pregnancy Hyperalimentation Obesity bypass surgery Cystic fibrosis Toxins ```
28
Steatosis (fatty liver) is the precursor for
Significant chronic disease
29
Steatosis (fatty liver) may lead to ____ in some patients
Hepatocellular carcinoma (HCC)
30
Steatosis (fatty liver) deposits may be ____ or _____
Focal or diffuse
31
Mild Steatosis (fatty liver) has
Minimal diffuse increase in hepatic echogenicity
32
Moderate Steatosis (fatty liver) has (2)
Moderate diffuse increase in hepatic echogenicity Slightly impaired visualization of intrahepatic vessels and diaphragm
33
Severe Steatosis (fatty liver) has (4)
Increase in echogenicity Poor penetraion of posterior liver Poor to no visualization of hepatic vessels and diaphragm Hepatomegally often present
34
3 other sonographic appearances of fatty liver
Focal fatty infiltration Fatty sparing Focal fat
35
What do we see with focal fatty infiltration
Regions of increase echogenicity in background of normal liver Can mimic a mass
36
Fatty sparing appears as
Islands of normal liver parenchyma appear as hypoechoic masses within a dense fatty infiltrated liver
37
Sonographic appearance of Steatosis (fatty liver) (4)
Rapid change in appearance and resolution over 6 days No mass effect No liver contour abnormality Focal fat appear rounded, nodular or interspersed
38
4 other tests for testing Steatosis (fatty liver)
CT for low attenuation areas Contrast enhanced to differentiate fatty from neoplasia MRI - distinguish diffuse from focal fatty infiltration Nuclear medicine scintigraphy