Flashcards in Lung Cancer Deck (15):
What are the 2 types of Lung ca?
Small Cell (15%)
Non-small Cell (85%)
What are the subtypes of NSCLC?
1. Adenocarcinoma (40%)
2. Squamous cell carcinoma
3. Large cell carcinoma
In what part of the lung is Lung Adenocarcinoma usually located?
Increased occurrence d/t cigarette filters which cause deeper inhalation
In what part of the lung is SCC usually located?
Central region of the lungs
What is limited stage SCLC?
30% of SCLC cases
Located on 1 side /1 lung
Can include nodes above
Can be tx'd with 1 XRT portal
What is extensive stage SCLC?
70% of SCLC cases
Mets outside of originating lung
Must be treated with >1 XRT field
Characteristics of SCLC
Rapid doubling time
High growth fraction
Early, widespread mets
Large hilar mass
Bulky CENTRAL adenopathy
SCLC often presents with?
-ACTH (cushings syndrome)
-ADH (hyponatremia )
What is a Pancos tumor and presentation?
Also called superior sulkis tumor
High apical tumor; invades brachial plexus
1. Upper shoulder, back, chest pain
2. Facial weakness
Treatment of NSCLC
Types of surgery
Targeted Therapy types for NSCLC
EGFR (often present in adenocarcinoma)
VEGF (Avastin w/ chemo)
Treatment for SCLC
Limited SCLC- Chemo and XRT
-better cure rate
-responsive but relapse is common
-cure is rare
Common sites for metastasis of lung cancer
1. Regional nodes