Lung Transplantation Flashcards Preview

Unit 4: Path - The Lung > Lung Transplantation > Flashcards

Flashcards in Lung Transplantation Deck (4):
1

A patient who underwent a lung transplant is experiencing rejection. A biopsy is shown below. What is the condition called? Describe the process.


Obliterative bronchiolitis; Bronchiole is virtually entirely obliterated by concentric fibrosis

2


What condition is common in long-term lung transplant survivors? Cause?


Bronchiectasis probably due to poor perfuse, denervation, and recurrent airway infection

3


What are the most common fungal pneumonias in those with lung transplants? Viral?


Candida and Aspergillus; CMV

4


In patients who survive > 30 days 3-8% develop what disorder? Describe pathogenesis


Lymphoproliferative disorders owing to uncontrolled proliferation of EBV-infected lymphocytes as a result of immunosuppression by cyclosporine