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Principles of Disease > Lymph > Flashcards

Flashcards in Lymph Deck (16)
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1
Q

What are the main functions of the lymphatic system?

A

Drainage fo fluid
Immunity
Absorbed fat transport from gut
Return of plasma/plasma proteins

2
Q

How is lymph composed?

A

Fluid and plasma proteins only, but gains lymphocytes as it flows and fats in the small intestine.

3
Q

What is lymph flow dependant on?

A

Muscle contraction
Pressure changes
Gravity

4
Q

Why is lymph flow unidirectional?

A

Valves

5
Q

Why does fluid flow into extracellular spaces increase during infection?

A

Accumulation of proteins through osmosis.

6
Q

Where are the acquired immunity functions of lymph located?

A

Lymph nodes.

7
Q

What structure can lymph nodes have?

A

Isolated

Grouped

8
Q

What are the secondary lymphoid follicles?

A

Germinal centres.

9
Q

Where are deep lymph nodes located?

A

Abdomen; associated with mesentries.

10
Q

What are superficial lymph nodes?

A

Less prominent; many located at base of lower limb.

11
Q

Describe some lymphatic pathologies.

A

Primary tumours- Lymphoma
Secondary tumours- metastasis of other tumours
Mononucleotic infection (TB/Glandular fever)
Inflammatory hyperplasia

12
Q

How is initial drainage of lymphatic fluid characterised?

A

Symmetrically- ultimately, it all collects in 2 ducts.

13
Q

What does deep lymphatic drainage follow?

A

Route of arterial supply.

14
Q

Where do the 2 lymphatic ducts empty into the venous system?

A

Jugular / subclavian junction.

15
Q

How does the lymphatic system function in immunity?

A

Lymphocyte generation.

16
Q

What is the spleen?

A

Largest lymphatic organ functioning in filter of blood.