lymphatic system Flashcards

1
Q

what is the job of the lymphatic system?

A

to return fluids that leak from vascular
system back to the blood

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2
Q

how many litres of blood per day is filtrated?

A

20 letres, (17L is taken back up into blood system whilst 3L is kept in interstitial space)

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3
Q

what does interstitial fluid do?

A

allows nutrients, waste and gas exchange between blood and cells

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4
Q

Lymphatic vessels return ??? and plasma proteins to blood

A

lymph fluid

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5
Q

which way/where to does lymph flow?

A

flows unidirectionally to the heart

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6
Q

lymphatic capillaries collect ??? from what space?

A

Collect lymph from interstitial space

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7
Q

how permeable ar lymphatic capillaries? why?

A

VERY permeable. to allow exchange and facilitate absorption

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8
Q

TRUE or FALSE: Endothelial cells tightly overlap forming one-way
mini-valves

A

FALSE, they are VERY LOOSE

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9
Q

what provides structural support?

A

collagen filaments

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10
Q

why do lymphatic capillaries need structural support?

A

so that interstitial fluid pressure doesn’t
collapse lymphatic capillaries

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11
Q

do proteins enter blood for absorbance?

A

No, they too big so enter lymph system instead.

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12
Q

what triggers lymphatic capillaries to widen? WHY?

A

inflammation and disease. To take up cell debris, pathogens, and cancer cells

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13
Q

what do lymph nodes filter?

A

lymph nodes filter the lymph fluid passing through them.

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14
Q

what are the specialised lymphatic capillaries in the small intestine called?

A

lacteals

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15
Q

how is fat absorbed into blood? not through normal capillaries

A

fat is broken down and absorbed through the lymphatic systems lacteals

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16
Q

what do lymphatic capillaries drain into?

A

lymphatic collecting vessels

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17
Q

What do superficial lymphatic collecting vessels travel with?

A

Collecting vessels in the skin travel with superficial veins

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18
Q

What do deep lymphatic collecting vessels travel with?

A

Deep vessels travel
with deep arteries

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19
Q

what has thinner walls and more valves? veins or collecting vessels?

A

lymphatic collecting vessels

20
Q

what are lymphatic trunks?

A

the union of lymphatic vessels

21
Q

what are the two lymphatic ducts

A

Right lymphatic duct and the Thoracic
duct which arises from the cisterna chyli

22
Q

which duct drains the collecting vessels and trunks from the right arm and the right side of the head and thorax

A

the right lymphatic duct

23
Q

which duct arises from the cisterna chyli and drains the rest of the body

A

the thoracic duct

24
Q

what do the lymphatic ducts empty their lymph into?

A

the venous system at the junction of the internal jugular and subclavian veins on its own side of the body

25
how is lymph propelled through the body?
milking action of skeletal muscle, pulsations of nearby blood vessels, smooth muscle contractions in walls of lymphatic vessels
26
Lymphedema is caused when ??? is blocked
lymphatic vasculature
27
Lymphatic filariasis is when a ??? lives in lymph system
a parasitic worm
28
what are lymphoid cells called?
lymphocytes.
29
there are two types of lymphocytes, ??? and ???
T-cells and B-cells
30
what do T cells and B cells protect against?
antigens. eg foreign material, bacteria, viruses, toxins, etc
31
What do B-cells produce?
plasma cells that secrete antibodies
32
T cells can destroy and attack foreign cells, but can also Control / manage the immune response by secreting:
secreting chemicals that signal other immune cells into defense, e.g., multiplication of B cells
33
reticular connective tissue comprises what?
Lymphatic tissue: a loose connective tissue
34
nodules are solid, spherical bodies of tightly packed reticular fibres and lymphoid cells, also known as:
lymphatic follicles
35
TRUE or FALSE: Diffuse lymphatic tissue: scattered reticular fibres in every body organ
TRUE
36
where do lymph nodes cluster most in the body?
near the body surface in inguinal, axillary, and cervical regions
37
the germinal centre found in lymph nodes contain what type of cell?
B-cells
38
what does the cortex of a lymph node contain?
contains dendritic cells surrounding follicles with germinal centres, heavy with dividing B cells. Also T-cells on a very deep level
39
the spleen is the site of ??? proliferation and ???
lymphocyte proliferation and immune surveillance and response
40
what contains lymphocytes, macrophages, and huge numbers of erythrocytes
the spleen
41
what stores breakdown products from Red Blood Cells for late ruse? eg iron
the spleen
42
what type of pulp sits around the central arteries in the spleen?
white pulp
43
splenic cords (reticular connective tissue) that surround venous sinuses in the spleen makes up which pulp?
red pulp
44
TRUE or FALSE: the tonsils are made up of lymphatic tissue
TRUE
45
what is the site for T-cell lymphocyte maturation?
the thymus