Lymphomas

Question 1

Lymphomas are the primary cancers of the _______ system?

Answer 1

Lymphoreticular

Question 2

What are the two main categories of lymphomas?

Answer 2

Hodgkin’s Lymphoma and Non-Hodgkin’s Lymphoma (NHL)

Question 3

Who discovered Hodgkins Lymphoma and when?

Answer 3

Thomas Hodgkins and 1832

Question 4

Between Hodgkin’s and Non-Hodgkin’s, which has a predictable pattern of spread?

Answer 4

Hodgkin’s Lymphoma

Question 5

What type of cells are found in the lymphatics of Hodgkins Lymphatics?

Answer 5

Reed Sternberg Cell

Question 6

`The lymphatic system works along what type of system?

Answer 6

Circulatory

Question 7

What is the function of the lymphatics system?

Answer 7

Transport nutrients and removal of wastes

Question 8

Blood cells are often released through lymphatics, what type of blood cells are those?

Answer 8

Red Blood Cells

Question 9

Some portions of the blood produce lymph. True or False?

Answer 9

True

Question 10

What structures are apart of the lymphatics system?

Answer 10

Nodes, Lymph Fluids and Lymphatic Organs

Question 11

What is the primary function of lymph nodes?

Answer 11

Production of lymphocytes and Filtration of foreign particles

Question 12

What are the 5 major lymphatic organs?

Answer 12

Spleen, Thymus, Tonsils, Adenoids and Bone Marrow

Question 13

What are the two types of Lymphocytes?

Answer 13

T and B Lymphocytes

Question 14

Where do lymphocytes develop?

Answer 14

Bone Marrow

Question 15

Where do Lymphocytes mature?

Answer 15

Lymphatic organs

Question 16

What type of cells are recycled in the spleen?

Answer 16

Red Blood Cells

Question 17

Red Blood Cells are recycled by what organ?

Answer 17

Spleen

Question 18

Lymphoreticular tumors occur more in women. True or False?

Answer 18

False, it occurs more in Men

Question 19

What is the age range in which lymphomas are most commen?

Answer 19

20-34

Question 20

In what stage of life are risk for lymphomas most high?

Answer 20

Adolescence and early adulthood

Question 21

What is the five year survival rate of Lymphomas?

Answer 21

87%

Question 22

What are some causes to be associated with lymphomas? (4 answers)

Answer 22

Defective T-Cell Function, Possible link to Epstein-Barr Virus/Mononucleosis, Family History, and HIV

Question 23

What are some prognostic indicators for lymphoma? (10 answers)

Answer 23

Staging at time of diagnosis, reproductive factors, Alkylating agents, age, presence of B symptoms, number of sites, lower abdominal involvement, splenic involvement, elevated serum markers and erythrocyte sedimentation rates

Question 24

What is the clinical presentation of lymphoma?

Answer 24

Painless Mass

Question 25

Where do the painless masses of lymphoma commonly seen?

Answer 25

Neck (Cervical), S'Clav, and mediastinal

Question 26

Where do most lymphomas occur?

Answer 26

Above the diaphragm

Question 27

What percentage of people experience B-Symptoms?

Answer 27

1/3

Question 28

What are B Symptoms?

Answer 28

Fever (>100), Drenching night sweats, 10% weight loss in less than 6 months

Question 29

What are some of the occasional symptoms of B symptoms?

Answer 29

Alcohol induced pain and Pruritus

Question 30

What is Pruritus?

Answer 30

unpleasant sensation of the skin that provokes the urge to scratch

Question 31

What are some physical detections for those that have lymphomas?

Answer 31

Enlarged nodes, Mediastinal mass, B Symptoms, Enlarged Spleen or abdomen, Bony tenderness, Pleural effusion, Groin nodes

Question 32

What test are completed for lymphoma?

Answer 32

Serum Alkaline Phosphatase levels, radiographic studies, bone marrow biopsy

Question 33

What is the a sign of lymphoma?

Answer 33

Reed Sternberg Cells being present in the lymphatics

Question 34

What is a pathological indication of nodular lymphocyte predominant Hodgkins lymphoma?

Answer 34

Reed Sternberg Variant which has a distinct popcorn cell shaped nucleus

Question 35

Who are the primary demographic that NLPHL affect?

Answer 35

Men, specifically 30-50

Question 36

What are the common node involved in NLPHL?

Answer 36

Nodes in the neck and axilla

Question 37

What percentage of lymphomas, are Classic Hodgkins Lymphoma?

Answer 37

95%

Question 38

What are the 4 subtypes of Hodgkins Lymphoma?

Answer 38

NSHL (Nodular Sclerosis), MCHL (Mixed cellularity) , LRHL (Lymphocyte-rich) , LDHL (Lymphocyte-depleted)

Question 39

What is the most common of the Hodgkins lymphomas?

Answer 39

MCHL (Mixed cellularity)

Question 40

Which Hodgkins lymphoma has the worst prognosis?

Answer 40

LDHL (Lymphocyte-depleted)

Question 41

What staging system do lymphoma's utilize?

Answer 41

Ann Arbor Staging System

Question 42

What is the difference between Stage I and II & Stage III and IV?

Answer 42

Stage I and II have nodes on the same side of the diaphragm, while Stage II has nodes on both side of the diaphragm and Stage IV is widespread

Question 43

What are the 4 categories that the lymphomas can be placed into during staging?

Answer 43

A, B, E, S

Question 44

What is Category A of lymphomas?

Answer 44

There are no B symptoms present

Question 45

What is Category B of lymphomas?

Answer 45

There are B symptoms present

Question 46

What is Category E of lymphomas?

Answer 46

There are HL cells found outside the lymphatics

Question 47

What is Category S of lymphomas?

Answer 47

There are HL cells found in the spleen