Penile and Urethra Cancer

Question 1

What percentage of male cancer does penile cancer account for?

Answer 1

Less than 1%

Question 2

What is an early in life measure that can prevent penile cancer?

Answer 2

Circumcision

Question 3

What are three contributing factors to penile cancer?

Answer 3

Smegma and Phimosis and HPV

Question 4

What is Smegma?

Answer 4

White secretion that collects under the prepuce of foreskin

Question 5

What is Phimosis?

Answer 5

Narrowing of the opening of the prepuce

Question 6

What five factors could contribute to Urethra Cancer?

Answer 6

Chronic Irritation, Infections, STDS (HPV16), Stricture

Question 7

What is the average age range for men that have urethra cancer?

Answer 7

58-60

Question 8

What percentage of urethra cancer occurs in men under 40?

Answer 8

10%

Question 9

What is the primary prognostic indicator of penile cancer? ( 2 answers)

Answer 9

Extent of Lesion and Nodal Involvement

Question 10

What is the long-term survival rate for tumors free nodal involvement?

Answer 10

80-90%

Question 11

What is the long-term survival rate for inguinal nodal involvement?

Answer 11

40-50%

Question 12

What is the long-term survival rate for inguinal node + pelvic node involvement?

Answer 12

less than 20%

Question 13

Bulbomembraneous tumors have a poor prognosis. True or False?

Answer 13

True

Question 14

Distal urethra lesions have a similar prognosis to what cancer?

Answer 14

Penile

Question 15

prostatic urethra lesions have a similar prognosis to what cancer?

Answer 15

Bladder

Question 16

What are the three tissues within the penis?

Answer 16

TWO Corpus Cavernosa and Corpus Spongiosum

Question 17

What nodes do the prepuce and skin of the shaft drain into? (1 answer)

Answer 17

Superficial Inguinal Nodes

Question 18

What nodes do the penile urethra and fossa navicularis drain into? (2 answers)

Answer 18

deep and superficial inguinal nodes

Question 19

What three possible lymphatic routes can the bulbomembranous and prostatic urethra drain to?

Answer 19

External iliacs, obturator and internal Iliac’s or pre-sacral nodes

Question 20

What does penile cancer present as? (2 answers)

Answer 20

Infection and Foul smell

Question 21

What does urethral cancer present as? (5 answers)

Answer 21

Obstructive symptoms, tenderness, dysuria, urethral discharge, and occasional hematuria

Question 22

What is the common pathology of penile cancer AND Urethral cancer?

Answer 22

Squamous cell carcinoma

Question 23

What is the purpose of a biopsy for penile cancer?

Answer 23

determine histology

Question 24

What is the purpose of a CT for penile cancer?

Answer 24

determine nodal involvement

Question 25

What two procedures are completed in the process of detecting urethral cancer?

Answer 25

Cystoscopy and Urethroscopy

Question 26

What staging system is used for penile cancer?

Answer 26

TNM

Question 27

What is the common site of regional metastasis for penile cancer?

Answer 27

Inguinal nodes

Question 28

Distal mets from penile cancer are common. True or False?

Answer 28

False, they are uncommon

Question 29

What percentage of urethral cancers are SCC?

Answer 29

80%

Question 30

What percentage of prostatic urethral cancers are Transitional Cell Carcinoma?

Answer 30

90%

Question 31

What location of the urethra region are adenocarcinomas most prevalent?

Answer 31

Bulbomembranous Urethra

Question 32

What is the common site of metastasis for bulbomembranous and prostatic urethra cancer?

Answer 32

Pelvic nodes

Question 33

What are four methods of treatment for penile cancer?

Answer 33

Surgery, Chemotherapy, Radiation and Brachytherapy

Question 34

What is the treatment of choice for distal urethral tumors?

Answer 34

Total or Partial Penectomy

Question 35

What is the treatment of choice for proximal urethral lesions?

Answer 35

Total Penectomy with Prostatectomy and Cystectomy for very Proximal lesions

Question 36

What are some side effects to be expected from penile and urethral cancer treatment? (5 answers)

Answer 36

Erythema, Dry and Moist desquamation, Swelling of the shaft, Stricture and Ulceration

Question 37

What is the typical XRT dosage for penile cancer?

Answer 37

45-50 Gy with a boost of 60-70 Gy