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Flashcards in M/F Repro Deck (21):
1

Leydig cells produce

a. testosterone
b. lutenizing hormone
c. follicle stimulating hormone

a. testosterone

2

essential for growth and division of testicular germinal cells

a. testosterone
b. lutenizing hormone
c. follicle stimulating hormone

a. testosterone

3

stimulates Leydig cells to secrete Testosterone

a. testosterone
b. lutenizing hormone
c. follicle stimulating hormone

b. lutenizing hormone

4

stimulates Sertoli cells to convert spermatids to sperm

a. testosterone
b. lutenizing hormone
c. follicle stimulating hormone

c. follicle stimulating hormone

5

Definition of male infertility

below 20 million/ml, less than 50% motile or less than 60% normally conformed

Normal count is between 60 – 100 million/mL sperm

6

What is capacitation of sperm?

CHANGES that activate the sperm once it comes in contact with fluids of the female genital tract to ENABLE IT TO FERTILIZE THE OVUM

7

Major steps of regulaton of male reproductive function

GnRH released pulsatively -> LH release ->

LH stimulates secretion of testosterone in leydig cells by MOA of activating cAMP

FSH bind to sertoli cells -> secretion of spermatogenic substances MOA cAMP

8

What is necessary for spermatogenesis?

a. testosterone
b. lutenizing hormone
c. follicle stimulating hormone

a. testosterone
c. follicle stimulating hormone

9

Major parts of Follicular Phase

- increase of FSH and LH
- growth of follicles
- addition of theca cells that secrete estrogen

- FSH + estrogen increase LH receptors
- follicle with highest number of LH receptors matures
- other follicles undergo atresia due to falling levels of FSH

- increase estrogen causes LH surge
- LH surge caues theca cells to secrete progesterone

- ovum released

10

Theca cells secrete

estrogen
progesterone
FSH
LH

1) estrogen at begining of follicular phase

2) progesterone at end of follicular phase due to LH

11

Estrogen has what type of feedback on LH

positive
negative

Positive. Causes LH surge

12

Major parts of Luteal Phase

- LH convert theca cells to corpus luteum
- continues to secrete progesterone

- involution of corpus luteum 12 - 14 days after ovulation

- estrogen remains high
- negative feedback to anterior pituiatry
- FSH and LH fall

- low LH causes CL to degenerate
- CL is now corpus albicans

- lack of progeterone causes endometrium to degenerate and slough off

13

Parts of ovarian cycle

- follicular phase
- luteal phase

14

Parts of endometrial cycle

- proliferative phase
- secretory phase
- menstruation

15

Main hormone of proliferative phase

estrogen

16

Main hormone of secretory phase

estrogen and progeterone

17

What causes the vasospasms in menstruation?

prostaglandins

18

most potent of ovarian origin

a. b-estradiol
b. estrone
c. estriol

a. b-estradiol

19

adrenal androgen source of estrogen in the menopausal woman

a. b-estradiol
b. estrone
c. estriol

b. estrone

20

weakest, estrogen of pregnancy

a. b-estradiol
b. estrone
c. estriol

c. estriol

21

Systems affected by estrogen

- reproductive system
- bone
- liver
- cardio vascular
- CNS